8 documents found, page 1 of 1
Disrupted Spatial Organization of Cued Exogenous Attention Persists Into Adulth...
Pina Rodrigues, Ana; Castelo-Branco, Miguel; van Asselen, MariekePurpose: Abnormal exogenous attention orienting and diffused spatial distribution of attention have been associated with reading impairment in children with developmental dyslexia. However, studies in adults have failed to replicate such relationships. The goal of the present study was to address this issue by assessing exogenous visual attention and its peripheral spatial distribution in adults with developmen...
Neural Responses of the Anterior Ventral Occipitotemporal Cortex in Development...
Rodrigues, Ana Pina; Rebola, José; Pereira, Marcelino; van Asselen, Marieke; Castelo Branco, Miguel de Sá e SousaFor the past 2 decades, neuroimaging studies in dyslexia have pointed toward a hypoactivation of the ventral occipitotemporal cortex (VOTC), a region that has been closely associated to reading through the extraction of a representation of words which is invariant to position, size, font or case. However, most of the studies are confined to the visual word form area (VWFA), while recent studies have demonstrate...
A Novel Ecological Approach Reveals Early Executive Function Impairments in Hun...
Júlio, Filipa; Ribeiro, Maria J.; Patrício, Miguel; Malhão, Alexandre; Pedrosa, Fábio; Gonçalves, Hélio; Simões, Marco; van Asselen, MariekeIntroduction: Impairments in executive functions are common in neurogenetic disorders such as Huntington's disease (HD) and are thought to significantly influence the patient's functional status. Reliable tools with higher ecological validity that can assess and predict the impact of executive dysfunction in daily-life performance are needed. This study aimed to develop and validate a novel non-immersive virtua...
Visual Perception and Reading: New Clues to Patterns of Dysfunction Across Mult...
Rodrigues, Ana Pina; Rebola, José; Jorge, Helena; Ribeiro, Maria José; Pereira, Marcelino; van Asselen, Marieke; Castelo-Branco, MiguelPURPOSE. The specificity of visual channel impairment in dyslexia has been the subject of much controversy. The purpose of this study was to determine if a differential pattern of impairment can be verified between visual channels in children with developmental dyslexia, and in particular, if the pattern of deficits is more conspicuous in tasks where the magnocellular–dorsal system recruitment prevails. Additio...
The role of the amygdala and the basal ganglia in visual processing of central ...
Almeida, Inês; van Asselen, Marieke; Castelo-Branco, MiguelIn human cognition, most relevant stimuli, such as faces, are processed in central vision. However, it is widely believed that recognition of relevant stimuli (e.g. threatening animal faces) at peripheral locations is also important due to their survival value. Moreover, task instructions have been shown to modulate brain regions involved in threat recognition (e.g. the amygdala). In this respect it is also con...
Implicit contextual learning in prodromal and early stage Huntington's disease ...
van Asselen, Marieke; Almeida, Inês; Júlio, Filipa; Januário, Cristina; Campos, Elzbieta Bobrowicz; Simões, Mário; Castelo-Branco, MiguelHuntington's disease (HD) is a genetic neurodegenerative disorder affecting the basal ganglia. These subcortical structures are particularly important for motor functions, response selection and implicit learning. In the current study, we have assessed prodromal and symptomatic HD participants with an implicit contextual learning task that is not based on motor learning, but on a purely visual implicit learning...
Scanning Patterns of Faces do not Explain Impaired Emotion Recognition in Hunti...
van Asselen, Marieke; Júlio, Filipa; Januário, Cristina; Campos, Elzbieta Bobrowicz; Almeida, Inês; Cavaco, Sara; Castelo-Branco, MiguelIn the current study, we aimed to investigate the emotion recognition impairment in Huntington's disease (HD) patients and define whether this deficit is caused by impaired scanning patterns of the face. To achieve this goal, we recorded eye movements during a two-alternative forced-choice emotion recognition task. HD patients in pre-symptomatic (n = 16) and symptomatic (n = 9) disease stages were tested and th...
The role of the basal ganglia in implicit contextual learning: a study of Parki...
van Asselen, Marieke; Almeida, Inês; André, Rui; Januário, Cristina; Gonçalves, António Freire; Castelo-Branco, MiguelImplicit contextual learning refers to the ability to memorize contextual information from our environment. This contextual information can then be used to guide our attention to a specific location. Although the medial temporal lobe is important for this type of learning, the basal ganglia might also be involved considering its role in many implicit learning processes. In order to understand the role of the ba...