Encontrados 2 documentos, a visualizar página 1 de 1
Earlier initiation of antiretroviral treatment coincides with an initial contro...
Vinken, Lore; Katrien, Fransen,; Cuypers, Lize; Alexiev, Ivailo; Balotta, Claudia; Laurent, Debaisieux,; Carole, Seguin-Devaux,; Sergio Garcìa, Ribas,Human immunodeficiency virus type 1 (HIV-1) non-B subtype infections occurred in Belgium since the 1980s, mainly amongst migrants and heterosexuals, whereas subtype B predominated in men-having-sex-with-men (MSM). In the last decade, the diagnosis of F1 sub-subtype in particular has increased substantially, which prompted us to perform a detailed reconstruction of its epidemiological history. To this purpose, t...
Quantifying next generation sequencing sample pre-processing bias in HIV-1 comp...
Vrancken, Bram; Trovão, Nídia Sequeira; Baele, Guy; Van Wijngaerden, Eric; Vandamme, Anne Mieke; van Laethem, Kristel; Lemey, PhilippeGenetic analyses play a central role in infectious disease research. Massively parallelized “mechanical cloning” and sequencing technologies were quickly adopted by HIV researchers in order to broaden the understanding of the clinical importance of minor drug-resistant variants. These efforts have, however, remained largely limited to small genomic regions. The growing need to monitor multiple genome regions fo...