6 documents found, page 1 of 1
Sleep and cardiometabolic comorbidities in the obstructive sleep apnoea-COPD ov...
van Zeller, M; Basoglu, OK; Verbraecken, J; Lombardi, C; McNicholas, WT; Pepin, JL; Steiropoulos, P; Sliwinski, P; Correia, D; Bonsignore, MRAim The impact of obstructive sleep apnoea (OSA)-COPD overlap syndrome (OVS) on sleep quality and cardiovascular outcomes has not been fully explored. We aimed to compare clinical and polysomnographic characteristics of patients with OVS versus patients with OSA, and to explore pathophysiological links between OVS and comorbidities. Study design and methods This cross-sectional analysis initially included data ...
Severe Asthma in the Era of COVID-19: A Narrative Review
Gaspar-Marques, J; van Zeller, M; Carreiro-Martins, P; Chaves Loureiro, CIntroduction and objectives: Severe asthma management during the coronavirus disease 2019 (COVID-19) pandemic is a challenge and will continue to be, at least in the next few months, as herd immunity is still a mirage. A lot has to be learned about how COVID-19 affects underlying diseases, and severe asthma is no exception. Methods: Narrative review of papers available until February 2021 in PubMed and Google S...
Clinical and Molecular Markers in COPD
Gonçalves, I; Guimarães, MJ; van Zeller, M; Menezes, F; Moita, J; Simão, PChronic obstructive pulmonary disease (COPD) is a complex and heterogeneous disease, and there is a clinical need for validated markers and biomarkers that can contribute to the assessment of patients, risk prediction, treatment guidance, and assessment of response. Although according to the 2018 GOLD guidelines clinically useful biomarkers for COPD patients in stable condition have yet to be identified, severa...
The Portuguese Severe Asthma Registry: Development, Features, and Data Sharing ...
Sá-Sousa, A; Fonseca, JA; Pereira, AM; Ferreira, A; Arrobas, A; Mendes, A; Drummond, M; Videira, W; Costa, T; Farinha, P; Soares, J; Rocha, PThe Portuguese Severe Asthma Registry (Registo de Asma Grave Portugal, RAG) was developed by an open collaborative network of asthma specialists. RAG collects data from adults and pediatric severe asthma patients that despite treatment optimization and adequate management of comorbidities require step 4/5 treatment according to GINA recommendations. In this paper, we describe the development and implementation ...
The Portuguese Severe Asthma Registry: Development, Features, and Data Sharing ...
Sá-Sousa, A; Fonseca, JA; Pereira, AM; Ferreira, A; Arrobas, A; Mendes, A; Drummond, M; Videira, W; Costa, T; Farinha, P; Soares, J; Rocha, PThe Portuguese Severe Asthma Registry (Registo de Asma Grave Portugal, RAG) was developed by an open collaborative network of asthma specialists. RAG collects data from adults and pediatric severe asthma patients that despite treatment optimization and adequate management of comorbidities require step 4/5 treatment according to GINA recommendations. In this paper, we describe the development and implementation ...
5-Years APAP adherence in OSA patients - Do first impressions matter?
van Zeller, M; Severo, M; Santos, AC; Drummond, MBackground: Although continuous positive airway pressure (CPAP) is effective in treating obstructive sleep apnoea (OSA), inadequate adherence remains a major cause of treatment failure. This study aimed to determine long term adherence to auto adjusting-CPAP (APAP) and its influencing factors including the role of initial compliance. Methods: Eighty-eight male patients with newly diagnosed moderate/severe OSA w...