11 documents found, page 1 of 2
Impact of the COVID-19 pandemic on laboratory diagnosis of tuberculosis in sout...
Quaresma de Souza, Mariana; Lemos Dal Pizzol, Juliana; Scholante Silva, Ana Bárbara; Furtado Gomes Riet Vargas, Felipe; Silva Brião, DeniseBackground and objectives: to understand the impact of the COVID-19 pandemic on tuberculosis (TB) diagnosis in different settings is essential to guide the establishment of appropriate TB control strategies. This study aimed to assess the influence of COVID-19 pandemic in laboratory diagnosis of TB in patients tested and diagnosed for TB. Methods: a data survey was carried out in the database of laboratories th...
Whole-genome sequencing as a tool for studying the microevolution of drug-resis...
Diniz, Jaciara; von Groll, Andrea; Unis, Gisela; Dalla-Costa, Elis Regina; Rosa Rossetti, Maria Lúcia; Vianna, Júlia Silveira; Ramos, Daniela FernandesTreatment of drug-resistant tuberculosis requires extended use of more toxic and less effective drugs and may result in retreatment cases due to failure, abandonment or disease recurrence. It is therefore important to understand the evolutionary process of drug resistance in Mycobacterium tuberculosis. We here in describe the microevolution of drug resistance in serial isolates from six previously treated patie...
Aspergillosis in albatrosses
Melo, Aryse Martins; Silva Filho, Rodolfo Pinho da; Poester, Vanice Rodrigues; Fernandes, Cristina Gevehr; von Groll, Andrea; Stevens, David AAspergillosis is a respiratory fungal disease of importance in captive marine birds. The aim of this study was to describe the occurrence of aspergillosis in Thalassarche melanophris during rehabilitation events and to identify the etiological agent. All the albatrosses that were received for rehabilitation and died within a 2-year period were included in the study. The proportionate mortality rate caused by as...
Molecular identification of Aspergillus isolates from Magellanic penguins
Melo, Aryse Martins; da Silva Filho, Rodolfo Pinho; Poester, Vanice Rodrigues; von Groll, Andrea; Stevens, David A.; Sabino, RaquelAspergillosis is an important disease in marine birds and has a mortality rate of 50% in Magellanic penguins (Spheniscus magellanicus) in captivity. Molecular biology allows the precise identification of Aspergillus to species level, which is important since cryptic species may show differences in their virulence attributes and in their antifungal susceptibility. This work aimed to perform molecular identificat...
Aspergillosis in free-ranging aquatic birds
Melo, Aryse Martins; Silva-Filho, Rodolfo Pinho da; Poester, Vanice Rodrigues; von Groll, Andrea; Fernandes, Cristina Gevehr; Stevens, David A.Due to the difficulty in the access to free-ranging birds, data regarding Aspergillus infections in wild avian species is rare compared to captive wild and domestic birds. Objective: report three cases of Aspergillus section Fumigati causing fungal disease in free-ranging aquatic birds, with the identification of the causal agent to the species level. Case reports: The diagnosis of aspergillosis was performed b...
CPLP-TB: a new tuberculosis transnational surveillance tool for the lusophone c...
Perdigão, João; Silva, Carla; Diniz, Jaciara; Pereira, Catarina; Machado, Diana; Ramos, Jorge; Silva, Hugo; Abilleira, Fernanda; Brum, ClariceTuberculosis (TB) remains a major health problem within the Community of Portuguese Language Speaking Countries (CPLP). Despite the marked variation in TB incidence across its member-states and continued human migratory flux between countries, a considerable gap in the knowledge on the Mycobacterium tuberculosis population structure and strain circulation between the countries still exists. To address this, we ...
Mycobacterium tuberculosis genetic diversity and drug resistance across Portugu...
Perdigão, João; Silva, Carla; Diniz, Jaciara; Pereira, Catarina; Machado, Diana; Ramos, Jorge; Silva, Hugo; Abilleira, Fernanda; Brum, ClariceBackground: Tuberculosis (TB) remains a major health problem within the Community of Portuguese Language Speaking Countries (CPLP). Despite the marked variation in TB incidence across its member-states and continued human migratory flux between countries, a considerable gap in the knowledge on the Mycobacterium tuberculosis population structure and strain circulation between the countries still exists. Material...
Aspergillosis in albatrosses
Melo, Aryse Martins; Silva Filho, Rodolfo Pinho da; Poester, Vanice Rodrigues; Fernandes, Cristina Gevehr; von Groll, Andrea; Stevens, David AAspergillosis is a respiratory fungal disease of importance in captive marine birds. The aim of this study was to describe the occurrence of aspergillosis in Thalassarche melanophris during rehabilitation events and to identify the etiological agent. All the albatrosses that were received for rehabilitation and died within a 2-year period were included in the study. The proportionate mortality rate caused by as...
Clonal expansion across the seas as seen through CPLP-TB database: a joint effo...
Perdigão, João; Silva, Carla; Diniz, Jaciara; Pereira, Catarina; Machado, Diana; Ramos, Jorge; Silva, Hugo; Abilleira, Fernanda; Brum, ClariceTuberculosis (TB) remains a major health problem within the Community of Portuguese Language Speaking Countries (CPLP). Despite the marked variation in TB incidence across its member-states and continued human migratory flux between countries, a considerable gap in the knowledge on the Mycobacterium tuberculosis population structure and strain circulation between the countries still exists. To address this, we ...
Tuberculosis across the seas: CPLP-TB - a joint effort in cataloguing mycobacte...
Perdigão, João; Silva, Carla; Diniz, Jaciara; Pereira, Catarina; Machado, Diana; Ramos, Jorge; da Silva, Fernanda; Brum, Clarice; Reis, Ana J.The Community of Portuguese Language Speaking Countries (CPLP) comprises nine countries across four continents, accounting for 7.2% of the world’s land area, and where tuberculosis (TB) is still a cause of public health concern. A marked variation in TB incidence (23 to 551 cases per 100 000 habitants) can be observed across the different member-states and, despite of this, a considerable gap in the knowledge o...