7 documents found, page 1 of 1
Pseudomonas aestus Isolation from the Nasal Cavity of a Cat with Chronic Rhinitis
Abreu, Raquel; Mouro, Sofia; Guerreiro, Joana F.; Sousa, Sílvia A.; Leitão, Jorge H.; Pissarra, Hugo; Cunha, Eva; Tavares, Luís; Oliveira, ManuelaThe Pseudomonas genus includes ubiquitous bacteria frequently described as animal and human opportunistic pathogens. A 9-year-old cat was referred for rhinoscopy at the Veterinary Hospital of the Faculty of Veterinary Medicine, University of Lisbon, Portugal, for an investigation of the chronic respiratory signs. Upon rhinoscopy, nasal and nasopharyngeal discharge were observed, and the nasal turbinates showed ...
Biochar supplementation affects the microbiome of recycled manure solids for co...
Guerreiro, Joana F.; Pires, Ana J.; Nunes, Mónica; Esteves, Ana; Chambel, Lélia; Pascoal, Pedro; Pereira, Marcelo; Fangueiro, David; Tavares, LuísThe widespread use of Recycled Manure Solids (RMS) as cow bedding material is not without risks, since cattle manure may act as a vehicle for pathogenic and antimicrobial resistant bacteria dissemination. Thus, our aim was to evaluate RMS-supplemented with a pine biochar produced in Portugal as a new cow bedding material, since the use of biochar has been shown to have the potential to mitigate the impact of re...
The Mössbauer effect using 57Fe-ferrabisdicarbollide ([o-57FESAN]−) : a glance ...
Buades, Ana B.; Pereira, Laura C. J.; Vieira, Bruno J. C.; Cerdeira, Ana C.; Waerenborgh, João C.; Pinheiro, Teresa; Matos, António P. A.Although a variety of cancers are initially susceptible to chemotherapy, they eventually develop multi-drug resistance. To overcome this situation, more effective and selective treatments are necessary using anti-tumour agents that act in two or more ways and offer greater therapeutic benefits over single-mechanism entities. In this study, we report on treating cancer with Na[3,3′-57Fe(1,2-C2B9H11)2], which off...
Broad Spectrum Functional Activity of Structurally Related Monoanionic Au(III) ...
Le Gal, Yann; Filatre-Furcate, Agathe; Lorcy, Dominique; Jeannin, Olivier; Roisnel, Thierry; Dorcet, Vincent; Fontinha, Diana; Francisco, DeniseThe biological properties of sixteen structurally related monoanionic gold (III) bis(dithiolene/diselenolene) complexes were evaluated. The complexes differ in the nature of the heteroatom connected to the gold atom (AuS for dithiolene, AuSe for diselenolene), the substituent on the nitrogen atom of the thiazoline ring (Me, Et, Pr, iPr and Bu), the nature of the exocyclic atom or group of atoms (O, S, Se, C(CN)...
Copper-64 Chloride Exhibits Therapeutic Potential in Three-Dimensional Cellular...
Pinto, Catarina I. G.; Bucar, Sara; Alves, Vítor H. P.; Fonseca, Alexandra; Abrunhosa, Antero J.; da Silva, Cláudia L.; Guerreiro, Joana F.Prostate cancer (PCa) is the second most common cancer type in men, and in advanced metastatic stages is considerable incurable. This justifies the need for efficient early diagnostic methods and novel therapies, particularly radiopharmaceuticals with the potential for simultaneous diagnosis and therapy (theranostics). We have previously demonstrated, using monolayer-cultured cells, that copper-64 chloride, a p...
Mitochondrial proteomics of the acetic acid – induced programmed cell death res...
Guerreiro, Joana F.; Marques, Maria Belém Sousa Sampaio; Soares, Renata; Coelho, Ana Varela; Leão, Cecília; Ludovico, Paula; Sá-Correia, IsabelVery high concentrations of acetic acid at low pH induce programmed cell death (PCD) in both the experimental model Saccharomyces cerevisiae and in Zygosaccharomyces bailii, the latter being considered the most problematic acidic food spoilage yeast due to its remarkable intrinsic resistance to this food preservative. However, while the mechanisms underlying S. cerevisiae PCD induced by acetic acid have been pr...
The genome sequence of the highly acetic acid-tolerant zygosaccharomyces bailii...
Leão, Cecília; Rodrigues, Fernando José dos Santos; Santos, Júlia; Mira, Nuno P.; Münsterkötter, Martin; Valada, Filipa Dias; Palma, MargaridaIn this work, it is described the sequencing and annotation of the genome of the yeast strain ISA1307, isolated from a sparkling wine continuous production plant. This strain, formerly considered of the Zygosaccharomyces bailii species, has been used to study Z. bailii physiology, in particular, its extreme tolerance to acetic acid stress at low pH. The analysis of the genome sequence described in this work ind...