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This paper address the post-entry performance of firms for seven regions in Portugal, at the NUTTII level, by investigating the structural characteristics of survival, using a semi-parametric method, during the period 1985 to 2007. In order to approach the prevalence of some stylized facts and determinants of new firm survival, a new entrepreneurship database was produced following the application of the Eurostat/OECD methodology to Quadros de Pessoal. In the semi-parametric estimation, survival is related to seven explanatory variables and sector and year dummies. The main contribution of this work is the application of an internationally comparable methodology to a linked employer-employee dataset, which provides a regional overview of the firm and survival dynamics over an extended period of time while guaranteeing regional, national and international comparability.