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Companies face an increasingly strict demanding and competitive environment. Firms that want stand out in the business world should create strategies to be, day after day, better when compared to with their competitors. Process management in companies is assumed as critical, given that in a constantly changing environment, the adaptation and efficient management of processes with a continuous improvement focus may bring remarkable benefits to the companies. As several studies have highlighted, the continuous improvement of the firm is dependent on the commitment of top management and its leadership. At the same time knowledge management practices are essential for this process. This study analyzes the effects of leadership in process management through knowledge management. Thus, using a sample of 187 companies, this investigation analyzed trough structural equation modeling the impact of this variables on process management efficiency. Despite having had some practical limitations, we find that leadership is a key variable in determining knowledge management. Furthermore, this research showed that knowledge management has influence over the management processes in companies from the viewpoint of continuous improvement.