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Human health may have several problems that occur when sleep disturbances are verified, causing a loss in the quality of life, autonomic dysfunction and decreased professional or academic performance. Objective: The aim is check if the ergonomic intervention can mean positive changes in the indices of back pain (BP) complains, quality of life (QOL) and sleep quality (SQ) in young adults. Methods: A sample of 21,560 observations (595 sleep hours) of 24 young adults (12 male military and 12 female undergraduate) were separated in three groups (Experimental [EG], Placebo [PG] and Control [CG]). The sleep behavior was classified into two Interaction Categories according to the iSEE methodology observation. For the carrying out, the Visual Analogue Scale, the abbreviated questionnaire of World Health Organization on quality of life and the Pittsburgh Sleep Quality Index was used before and after an ergonomic intervention program by physiotherapy. Results: EG improved self-perception of SQ (p = 0.008), QOL (p = 0.000), reduce the level of BP (p = 0.001) and change for an ideal posture while sleeping. Conclusion: The findings of this study allow us to suggest to health care professionals, in particular the rehabilitation professionals, new strategies for ergonomic postural behavior.