Detalhes do Documento

This research work aims to validate a new system that enables the fabrication of multimaterial 3D structures using poly(e-caprolactone) and sodium alginate for potential use in Tissue Engineering applications. To produce multi-material scaffolds for Tissue Engineering, accurate techniques are needed to obtain three-dimensional constructs with clinically appropriate size and structural integrity. This paper presents a novel biomanufacturing system which can fabricate 3D scaffolds with precise shape and porosity, through the control of all fabrication modules by an integrated computational platform. The incorporation of a clean flow unit and a camera makes it possible to produce scaffolds in a clean environment and provides a monitoring tool to analyse constructs during the production, respectively.