Author(s):
Asif, Muhammad ; Couto, Francisco M. ; Vicente, Astrid M.
Date: 2018
Persistent ID: http://hdl.handle.net/10400.18/5637
Origin: Repositório Científico do Instituto Nacional de Saúde
Subject(s): Autism Spectrum Disorder; Perturbações do Desenvolvimento Infantil e Saúde Mental; Autism Spectrum Disorder; Autism Spectrum Disorder; Perturbações do Desenvolvimento Infantil e Saúde Mental; Perturbações do Desenvolvimento Infantil e Saúde Mental
Description
Objectives: To identify clinically similar subgroups of individuals with ASD [To reduce ASD heterogeneous phenotype]; To find biological processes disrupted by rare CNVs targeting brain genes in ASD subjects [To maximize the reproducibility with other data sets]; To train a machine learning classifier for the clinical prediction of disease progression from genetic information in very young children [To facilitate clinical doctors in diagnosis]
