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Maternal depression and anxiety predicts the pattern of offspring symptoms during their transition to adulthood.

Author(s): Gonçalves, Helen ; Pearson, Rebecca M. ; Horta, Bernardo Lessa ; González Chica, David Alejandro ; Castilho, Euclides ; Damiani, Magda Floriana ; Lima, R. C. ; Gigante, Denise Petrucci ; Barros, Fernando C. ; Stein, Alan ; Victora, Cesar Gomes

Date: 2020

Origin: Oasisbr

Subject(s): Cohort study; Common mental disorder; Intergenerational; Mental health; Offspring; Cohort study; Cohort study; Common mental disorder; Common mental disorder; Intergenerational; Intergenerational; Mental health; Mental health; Offspring; Offspring


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Background. Episodes of depression and anxiety (D&A) during the transition from late adolescence to adulthood, particularly when persistent, are predictive of long-term disorders and associated public health burden. Understanding risk factors at this time is important to guide intervention. The current objective was to investigate the associations between maternal symptoms of D&A with offspring symptoms during their transition to adulthood. Method. Data from a large population-based birth cohort study, in South Brazil, were used. Prospective associations between maternal D&A and offspring risk of these symptoms during the transition to adulthood (18/19, 24 and 30 years) were estimated. Results. Maternal D&A in adolescence was associated with offspring symptoms across the transition to adulthood, associations were consistently stronger for females than for males. Daughters whose mothers reported D&A were 4.6 times (95% confidence interval 2.71–7.84) as likely to report D&A at all three time-points, than daughters of symptom-free mothers. Conclusions. Maternal D&A is associated with persistent D&A during the daughter’s transition to adulthood. Intervention strategies should consider the mother’s mental health.

Document Type Journal article
Language English
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