Document details

Development of Ti-15Zr-Mo alloys for applying as implantable biomedical devices

Author(s): Correa, D. R.N. ; Kuroda, P. A.B. [UNESP] ; Lourenço, M. L. [UNESP] ; Fernandes, C. J.C. [UNESP] ; Buzalaf, M. A.R. ; Zambuzzi, W. F. [UNESP] ; Grandini, C. R. [UNESP]

Date: 2018

Persistent ID: http://hdl.handle.net/11449/179725

Origin: Oasisbr

Subject(s): Biomaterial; Mechanical properties; Microstructure; Titanium alloys; Biomaterial; Biomaterial; Mechanical properties; Mechanical properties; Microstructure; Microstructure; Titanium alloys; Titanium alloys


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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

In this study, the effect of molybdenum content in Ti-15Zr-based alloys (wt%) was analyzed in terms of crystalline structure, microstructure, selected mechanical properties, and cytotoxicity. The samples were produced by argon arc-melting followed by hot rolling and heat treatment processes. The crystalline structure and microstructure were dependent of both alloying elements (zirconium and molybdenum). Ti-15Zr alloy displayed only laths of α′ phase, while the alloys up to Ti-15Zr-10Mo exhibited different proportions of α′ α” and β phases. Molybdenum content higher than 12.5 wt% fully stabilized the β phase. Vickers microhardness values of Ti-15Zr-Mo alloys were higher than those of CP-Ti due to solid solution and phase precipitation strengthening. Young's modulus values of Ti-15Zr-Mo alloys were lower than those of CP-Ti due to β phase stabilization. Cytotoxicity levels of Ti-15Zr-Mo alloys were within a tolerable range for biomedical purposes. In addition, we observed molybdenum content in Ti-15Zr-based alloys promoted an increase on pre-osteoblast adhesion up to 3 h of adhesion's time. Thus, Ti-15Zr-15Mo alloy presented better combination of properties than some traditional metallic biomaterials.

IFSP – Federal Institute of Education Science and Technology

UNESP – Univ Estadual Paulista Laboratório de Anelasticidade e Biomateriais

USP - Universidade de São Paulo Faculdade de Odontologia Departamento de Ciências Biológicas

UNESP - Univ Estadual Paulista Departamento de Química e Bioquímica

IBTN-Br - Institute of Biomaterials Tribocorrosion and Nanomedicine – Brazilian Branch

UNESP – Univ Estadual Paulista Laboratório de Anelasticidade e Biomateriais

UNESP - Univ Estadual Paulista Departamento de Química e Bioquímica

FAPESP: #2010/20440-7

FAPESP: #2012/22742-6

FAPESP: #2014/06.221-1

FAPESP: #2014/22689-3

FAPESP: #2015/00851-6

CNPq: #307.279/2013-8

CNPq: #481.313/2012-5

Document Type Journal article
Language English
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