Description
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Purpose: To investigate the effect of high-intensity interval training (HIIT) versus moderate-intensity continuous exercise training (MICE) on hemodynamic and functional variables in individuals with Parkinson's disease. Methods: Twenty participants (13 men) were randomly assigned to a thrice-weekly HIIT (n = 12) or MICE (n = 8) for 12 weeks. Hemodynamic (resting heart rate and blood pressure, carotid femoral pulse wave velocity, endothelial reactivity, and heart rate variability) and functional variables (5-time sit-to-stand, timed up and go, and 6-min walking tests) assessed before and after training. Results: Demographic, hemodynamic and functional variables were similar between groups at baseline. Endothelial reactivity tended to increase after HIIT, but not after MICE, resulting in improved level (similar to 8%, P < .01) of this variable in HIIT versus MICE during follow-up. Six-minute walking test improved after HIIT (10.4 +/- 3.8%, P < .05), but did not change after MICE. Sit to stand improved similarly after HIIT (27.2 +/- 6.1%, P < .05) and MICE (21.5 +/- 5.4%, P < .05). No significant changes were found after HIIT or MICE in any other variable assessed. Conclusion: These results suggest that exercise intensity may influence training-induced adaptation on endothelial reactivity and aerobic capacity in individuals with Parkinson's disease.
Sao Paulo State Univ UNESP, Sch Sci, Dept Phys Educ, Exercise & Chron Dis Res Lab ECDR, Bauru, SP, Brazil
Sao Paulo State Univ UNESP, Dept Phys Educ, Sch Sci, Human Movement Res Lab MOVI LAB, Bauru, SP, Brazil
Univ Sao Paulo, Sch Med, Heart Inst, Sao Paulo, Brazil
Univ Alberta, Fac Kinesiol Sport & Recreat, Edmonton, AB, Canada
Sao Paulo State Univ UNESP, Sch Sci, Dept Phys Educ, Exercise & Chron Dis Res Lab ECDR, Bauru, SP, Brazil
Sao Paulo State Univ UNESP, Dept Phys Educ, Sch Sci, Human Movement Res Lab MOVI LAB, Bauru, SP, Brazil
FAPESP: 2015/09259-2
FAPESP: 2016/08205-9
CNPq: 303399/2018-0
CNPq: 301957/2017-7
