Document details

Mycogenic metal nanoparticles for the treatment of mycobacterioses

Author(s): Simões, Marta Filipa ; Ottoni, Cristiane Angélica [UNESP] ; Antunes, André

Date: 2020

Persistent ID: http://hdl.handle.net/11449/199361

Origin: Oasisbr

Subject(s): Filamentous fungi; Metal nanoparticles (MNP); Mycobacterium tuberculosis (MTb); Mycogenic synthesis; Nontuberculous mycobacteria (NTM); Silver nanoparticles (AgNP); Tuberculosis (TB); Filamentous fungi; Filamentous fungi; Metal nanoparticles (MNP); Metal nanoparticles (MNP); Mycobacterium tuberculosis (MTb); Mycobacterium tuberculosis (MTb); Mycogenic synthesis; Mycogenic synthesis; Nontuberculous mycobacteria (NTM); Nontuberculous mycobacteria (NTM); Silver nanoparticles (AgNP); Silver nanoparticles (AgNP); Tuberculosis (TB); Tuberculosis (TB)


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Made available in DSpace on 2020-12-12T01:37:43Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-09-01

Mycobacterial infections are a resurgent and increasingly relevant problem. Within these, tuberculosis (TB) is particularly worrying as it is one of the top ten causes of death in the world and is the infectious disease that causes the highest number of deaths. A further concern is the on-going emergence of antimicrobial resistance, which seriously limits treatment. The COVID-19 pandemic has worsened current circumstances and future infections will be more incident. It is urgent to plan, draw solutions, and act to mitigate these issues, namely by exploring new approaches. The aims of this review are to showcase the extensive research and application of silver nanoparticles (AgNPs) and other metal nanoparticles (MNPs) as antimicrobial agents. We highlight the advantages of mycogenic synthesis, and report on their underexplored potential as agents in the fight against all mycobacterioses (non-tuberculous mycobacterial infections as well as TB). We propose further exploration of this field.

State Key Laboratory of Lunar and Planetary Sciences Macau University of Science and Technology, Avenida Wai Long

Bioscience Institute São Paulo State University (UNESP)

Bioscience Institute São Paulo State University (UNESP)

Document Type Journal article
Language English
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