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Made available in DSpace on 2020-12-12T02:01:44Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-04-01
Plasma electrolytic oxidation (PEO) has been a promising surface coating with better mechanical and antimicrobial parameters comparing to conventional treatment surfaces. This study evaluated the peri-implant bone repair using (PEO) surface coatings compared with sandblasted acid (SLA) treatment. For this purpose, 44 Wistar rats were ovariectomized (OVX-22 animals) or underwent simulated surgery (SS-22 animals) and received implants in the tibia with each of the surface coatings. The peri-implant bone subsequently underwent molecular, microstructural, bone turnover, and histometric analysis. Real-time PCR showed a higher expression of osteoprotegerin (OPG), receptor activator of nuclear kappa-B ligand (RANKL), and osteocalcin (OC) proteins in the SLA/OVX and PEO/SS groups (p < 0.05). Computed microtomography, confocal microscopy, and histometry showed similarity between the PEO and SLA surfaces, with a trend toward the superiority of PEO in OVX animals. Thus, PEO surfaces were shown to be promising for enhancing peri-implant bone repair in ovariectomized rats.
Department of Diagnosis and Surgery Sao Paulo State University-Unesp Aracatuba School of Dentistry
Technological Plasma Laboratory (LaPTec) Experimental Campus of Sorocaba Sao Paulo State University-Unesp
Department of Basic Science Sao Paulo State University-Unesp Aracatuba School of Dentistry
Department of Prosthodontics and Periodontology University of Campinas-Unicamp Piracicaba School of Dentistry
Dental Research Division Department of Periodontology and Oral Implantology University of Guarulhos (UnG)
Department of Diagnosis and Surgery Sao Paulo State University-Unesp Aracatuba School of Dentistry
Technological Plasma Laboratory (LaPTec) Experimental Campus of Sorocaba Sao Paulo State University-Unesp
Department of Basic Science Sao Paulo State University-Unesp Aracatuba School of Dentistry
