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On the mechanical biocompatibility of Ti-15Zr-based alloys for potential use as load-bearing implants

Author(s): Correa, D. R.N. ; Rocha, L. A. [UNESP] ; Donato, T. A.G. [UNESP] ; Sousa, K. S.J. [UNESP] ; Grandini, C. R. [UNESP] ; Afonso, C. R.M. ; Doi, H. ; Tsutsumi, Y. ; Hanawa, T.

Date: 2020

Persistent ID: http://hdl.handle.net/11449/201396

Origin: Oasisbr

Subject(s): Biomaterial; Load-Bearing implant; Mechanical properties; Ti-Zr-Mo alloy; Biomaterial; Biomaterial; Load-Bearing implant; Load-Bearing implant; Mechanical properties; Mechanical properties; Ti-Zr-Mo alloy; Ti-Zr-Mo alloy


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This study evaluated the mechanical properties and cytocompatibility of recently developed Ti-15Zr-based alloys with Mo addition for potential use as load-bearing implants. The phase composition and microstructure were changed by the alloying elements, being the β phase fully retained on the Ti-15Zr-10Mo and Ti-15Zr-15Mo samples. The TEM analysis showed that a small quantity of ω phase was precipitated on the samples with a high amount of Mo. Regarding the mechanical properties, the Ti-15Zr-10Mo sample presented high mechanical strength and large elongation (854»±»63»MPa and 18.7»±»2.8 %). However, the Ti-15Zr-15Mo sample exhibited better mechanical compatibility, due to its combination of low Young's modulus (75»±»1»GPa) and high Vickers microhardness (346»±»4»HV). Some dimple-type structures found along the fractured surface confirmed the ductile behavior of these samples. The MTT test indicated non-cytotoxic effects of all samples when in contact with osteoblastic cells (p»<»0.05). The wettability values of the samples were adequate for biomedical applications. The mechanical properties of the Ti-15Zr-15Mo sample were better than some commercial metallic biomaterials, which highlights its great potential for use as load-bearing implants.

IFSP Federal Institute of Education Science and Technology Grupo de Pesquisa em Materiais Metálicos Avançados

IBTN/BR Institute of Biomaterials Tribocorrosion and Nanomedicine Brazilian Branch

UNESP - Univ Estadual Paulista Laboratório de Anelasticidade e Biomateriais

UFSCar - University of São Carlos Department of Materials Engineering

Institute of Biomaterials and Bioengineering Tokyo Medical and Dental University

Research Center for Structural Materials National Institute for Materials Science

UNESP - Univ Estadual Paulista Laboratório de Anelasticidade e Biomateriais

Document Type Journal article
Language English
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