Autor(es):
Biasetto, Carolina R. [UNESP] ; Somensi, Andressa [UNESP] ; Sordi, Renata [UNESP] ; Chapla, Vanessa M. ; Ebrahimi, Samad N. ; Silva, Geraldo H. ; Teles, Helder L. ; Bolzani, Vanderlan da S. [UNESP] ; Young, Maria Cláudia M. ; Pfenning, Ludwig H. ; Araujo, Angela R. [UNESP]
Data: 2020
Identificador Persistente: http://hdl.handle.net/11449/201524
Origem: Oasisbr
Assunto(s): Acetylcholinesterase inhibitors.; Antifungal; Koninginin; Phomopsis stipata; Polyketides; Acetylcholinesterase inhibitors.; Acetylcholinesterase inhibitors.; Antifungal; Antifungal; Koninginin; Koninginin; Phomopsis stipata; Phomopsis stipata; Polyketides; Polyketides
Descrição
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Two new polyketides, named koninginin T (1) and U (2), were isolated from Phomopsis stipata - an endophytic fungus isolated from Styrax camporum Pohl. The structures of polyketides 1 and 2 were defined through the analysis of spectroscopic data. Antifungal and acetylcholinesterase inhibitory activities of these compounds were evaluated using TLC bioautographic assays. Compounds 1 and 2 displayed moderate antifungal activity and compound 1 showed acetylcholinesterase inhibitory activity.
Organic Chemistry Department São Paulo State University UNESP Chemistry Institute
Environmental Chemistry Federal University of Tocantins UFT
Department of Phytochemistry Medicinal Plants and Drugs Research Institute Shahid Beheshti University, Evin
Institute of Technological and Exact Sciences Federal University of Viçosa
Federal University of Mato Grosso Department of Biological Sciences
Institute of Botany of São Paulo
Phytopathology Department Federal University of Lavras
Organic Chemistry Department São Paulo State University UNESP Chemistry Institute
FAPESP: 03/02176-7
