Autor(es): Panontin, Juliane Farinelli ; Barbosa, Robson dos Santos ; Isaac, Vera [UNESP] ; Seibert, Carla Simone ; Scapin, Elisandra
Data: 2022
Identificador Persistente: http://hdl.handle.net/11449/223725
Origem: Oasisbr
Assunto(s): anti-ageing; DPPH; Mangabeira; phenolic compounds; phytocosmetics; anti-ageing; anti-ageing; DPPH; DPPH; Mangabeira; Mangabeira; phenolic compounds; phenolic compounds; phytocosmetics; phytocosmetics
Made available in DSpace on 2022-04-28T19:52:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-01
The goal of this work was to chemically characterise Hancornia speciosa extracts to develop an antioxidant serum formulation. Stem and bark extracts were prepared using 70% hydroethanol solution by Sohxlet and ultrasound assisted extraction. The content of total phenols, flavonoids, and antioxidant activity were evaluated, and chemical characterization was performed by HPLC -detector UV-VIS (SPD − 10 A). The formulation was developed with stem extract (0.250 mg/g) in hydroxyethylcellulose fluid gel. Stem extracts had higher total phenols and flavonoids, and higher antioxidant activity than bark extracts. The formulation presented low viscosity, a yellowish colour, 81.28% ± 0.14 of antioxidant activity. In the stability test, the physicochemical characteristics showed small variations, remaining more stable at a temperature of 5 °C, with an antioxidant activity of 64.81% ± 0.75. Therefore, the stem of H. speciosa has the potential to be used in antioxidant formulations.
Postgraduate Program in Environmental Sciences–Ciamb Federal University of Tocantins, TO
Postgraduate Program in Biodiversity and Biotechnology–BIONORTE Federal University of Tocantins, TO
School of Pharmaceutical Sciences São Paulo State University (Unesp), SP
School of Pharmaceutical Sciences São Paulo State University (Unesp), SP
