Document details

An insight on the role of photosensitizer nanocarriers for Photodynamic Therapy

Author(s): MESQUITA,MARIANA Q. ; DIAS,CRISTINA J. ; GAMELAS,SARA ; FARDILHA,MARGARIDA ; NEVES,MARIA G.P.M.S. ; FAUSTINO,MARIA AMPARO F.

Date: 2018

Origin: Oasisbr

Subject(s): Photodynamic therapy; Drug delivery; Liposomes; Silica nanoparticles; Gold nanoparticles; Polymeric micelles; Photodynamic therapy; Photodynamic therapy; Drug delivery; Drug delivery; Liposomes; Liposomes; Silica nanoparticles; Silica nanoparticles; Gold nanoparticles; Gold nanoparticles; Polymeric micelles; Polymeric micelles


Description

ABSTRACT Photodynamic therapy (PDT) is a modality of cancer treatment in which tumor cells are destroyed by reactive oxygen species (ROS) produced by photosensitizers following its activation with visible or near infrared light. The PDT success is dependent on different factors namely on the efficiency of the photosensitizer deliver and targeting ability. In this review a special attention will be given to the role of some drug delivery systems to improve the efficiency of tetrapyrrolic photosensitizers to this type of treatment.

Document Type Journal article
Language English
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