Detalhes do Documento

Vagus nerve stimulation may be a sound therapeutic option in the treatment of refractory epilepsy

Autor(es): Meneses,Murilo S. ; Rocha,Samanta F. B. ; Simão,Cristiane ; Santos,Heraldo Nei Hardt Laroca dos ; Pereira,Cleudi ; Kowacs,Pedro A.

Data: 2013

Origem: Oasisbr

Assunto(s): refractory epilepsy; epilepsy surgery; vagus nerve stimulation; refractory epilepsy; refractory epilepsy; epilepsy surgery; epilepsy surgery; vagus nerve stimulation; vagus nerve stimulation


Descrição

INTRODUCTION: Refractory epilepsy accounts for 20 to 30% of epilepsy cases and remains a challenge for neurologists. Vagus nerve stimulation (VNS) is an option for palliative treatment. OBJECTIVE: It was to study the efficacy and tolerability of VNS in patients implanted with a stimulator at the Curitiba Institute of Neurology (INC). METHODS: A case study of six patients with refractory epilepsy submitted to a VNS procedure at the INC in the last four years was described and discussed. RESULTS: Mean age at time of implantation was 29 years. Mean follow-up was 26.6 months. Seizure frequency decreased in all patients (40-50% (n=2) and >80% (n=4)). Three patients no longer required frequent hospitalizations. Two patients previously restricted to wheelchairs started to walk, probably because of improved mood. CONCLUSION: In this population, VNS proved to be a sound therapeutic option for treating refractory epilepsy.

Tipo de Documento Artigo científico
Idioma Inglês
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