Nas duas últimas décadas, a descentralização para o nível municipal de governo tem constituído uma das mais importantes estratégias de reforma das administrações públicas europeias. Muitos argumentos têm sido apontados a favor deste movimento. A maior proximidade à realidade local, o conhecimento mais profundo dos problemas e uma resposta mais adequada e proporcional, a otimização de custos e uma maior eficiênc...
Ochratoxin A (OTA) is a secondary metabolite produced by Penicillium and Aspergillus genera and is considered one of the most important mycotoxins occurring in animal and human food chains. Oxidative stress, inhibition of protein synthesis, disruption of calcium homeostasis, inhibition of mitochondrial respiration and DNA damage are some of OTA´s mechanisms of action causing teratogenicity, immunotoxicity, neur...
In this study a pure tone audiogram was developed under the Matlab® mathematical software. Audiogram measurements were performed to 35 subjects belonging to the female and male and aged between 10 and 88 years old. Some of the subjects with more advanced age had hearing problems over the course of age, however, none of them was carrying any type of hearing aid. The threshold of the Sound Pressure Level (SPL) wa...
This study aims to determine the physicochemical and fatty acids composition of Serra da Estrela cheese (SEC), as well as health-related lipid indices, like the atherogenic and thrombogenic indices, and to evaluate the influence of producer, geographical origin and production date. Design/methodology/approach – All 24 SEC produced between November 2017 and March 2018 were collected at selected certified produce...
The main objective of our work is to develop a tool (Graphical Simulator of Mathematical Algorithms - GraSMA) that can be used by teachers and students in the classes of Numerical Methods. GraSMA will screen the execution of mathematical algorithms coded in Octave. For the end user, the software is therefore a sequence of parameterized algorithms whose steps can be visualized graphically. To achieve it we try t...
Este trabalho teve como principal objectivo estudar a duração do anestro fisiológico pós-parto, em ovelhas da raça autóctone portuguesa Churra da Terra Quente e da raça exótica Ile de France, paridas no período de Inverno-Primavera e que amamentaram os seus borregos apenas durante dois períodos diários de meia hora cada. Para o efeito, utilizamos 24 ovelhas da raça Churra da Terra Quente e 16 da raça Ile de Fra...
Simple Summary Portugal has the largest chestnut tree plantation area for fruit production in Europe. The carpophagous pests Cydia splendana Hubner and Curculio elephas Gyllenhal are among the main pests that affect nut productivity and quality in the country. Their control is considered difficult due to the large size of the trees, and chestnut orchards are mostly located in mountain regions with high slopes. ...
Os cuidados a prestar em Saúde Reprodutiva constituem um conjunto diversificado de práticas que contribuem para a saúde e bem-estar reprodutivos através da prevenção e resolução de problemas, respondendo às necessidades específicas neste período de vida ¹. O abortamento espontâneo é identificado clinicamente em ¼ das mulheres, tendo uma ocorrência de uma em cada sete das gestações, nas primeiras 12 semanas2,3,4...
La característica esencial de un Estado de Derecho es el sometimiento de los diferentes poderes públicos al imperio de la ley. Por ello, tanto el poder ejecutivo, como el legislativo y el judicial están sometidos a la ley. Aún así no son los únicos, puesto que los ciudadanos y la propia Administración Pública no son ajenos a ello y también están obligados a cumplir la ley. El propio término Estado de Derecho ll...
Constructing a QSAR model involves several critical steps, including chemical structure preparation, molecular descriptor calculation and selection, and model development and validation. This study presents a comprehensive methodology for preparing QSAR models using freely open-source software tools. A detailed, stepby- step protocol outlines the entire process, from compound library preparation to statistical ...