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Development of an Online Multilingual Educational Programme for Parents of Dual...
Capranica, Laura; Guidotti, Flavia; Gonçalves, Carlos; Blondel, Laurence; Bovis, Matteo; Costa, Rute; Debois, Nadine; et al.There is a need for educational support structures to empower parents in sustaining talented athletes pursuing academic and sports careers (e. g., dual career). The present workdescribestheparticipatory designusedtodevelopaseriesofeducationalresources and the subsequent iterations used to evaluate the content of the EMPATIA online education programme for parents of dual-career athletes. Following an ethnographi...
Fatigue assessment of steel half-pipes bolted connections using local approaches
Öztürk, F.; Correia, J. A. F. O.; Rebelo, C.; De Jesus, A. M. P.; Silva, L. Simões daThis paper proposes a multiaxial fatigue assessment of a steel half-pipe bolted connection using a local energy-based approach. This bolted connection has been proposed for onshore wind turbine towers. A global linear-elastic model with beam elements for the onshore wind turbine tower was developed taking into account the stiffness of the joint. Damage equivalent fatigue loads were applied in global beam model....
Promoter hypermethylation of DNA repair genes MLH1 and MSH2 in adenocarcinomas ...
Gomes, A.; Silva, M. Reis; Alarcão, A.; Couceiro, P.; Sousa, V.; Carvalho, L.Five years survival of lung cancer is 16%, significantly lower than in prostate (99.9%), breast (88.5%) and colon (64.1%) carcinomas. When diagnosed in the surgical stage it increases to 50% but this group only comprises 14-16% of the cases. DNA methylation has emerged as a potential cancer-specific biomarker. Hypermethylation of CpG islands located in the promoter regions of tumour suppressor genes is now firm...
Cerebellar morphometric and spectroscopic biomarkers for Machado-Joseph Disease
Miranda, Catarina Oliveira; Nobre, Rui Jorge; Paiva, Vítor Hugo; Duarte, João Valente; Castelhano, João; Petrella, Lorena Itati; Sereno, JoséMachado-Joseph disease (MJD) or Spinocerebellar ataxia type 3 (SCA3) is the most common form of dominant SCA worldwide. Magnetic Resonance Imaging (MRI) and Proton Magnetic Resonance Spectroscopy (1H-MRS) provide promising non-invasive diagnostic and follow-up tools, also serving to evaluate therapies efficacy. However, pre-clinical studies showing relationship between MRI-MRS based biomarkers and functional pe...
Mineral Content and Volatile Profiling of Prunus avium L. (Sweet Cherry) By-Pro...
Nunes, Ana R.; Gonçalves, Ana C.; Pinto, Edgar; Amaro, Filipa; Flores-Félix, José D.; Almeida, Agostinho; Pinho, Paula Guedes de; Falcão, AmílcarLarge amounts of Prunus avium L. by-products result from sweet cherry production and processing. This work aimed to evaluate the mineral content and volatile profiling of the cherry stems, leaves, and flowers of the Saco cultivar collected from the Fundão region (Portugal). A total of 18 minerals were determined by ICP-MS, namely 8 essential and 10 non-essential elements. Phosphorus (P) was the most abundant mi...
Nursing Students' Perceptions on Healthcare-Associated Infection Control and Pr...
Parreira, Pedro; Santos-Costa, Paulo; Pardal, João; Neves, Teresa; Bernardes, Rafael A.; Serambeque, Beatriz; Sousa, Liliana B.; Graveto, JoãoHealthcare-associated infections (HAI) are one of the major concerns worldwide, posing significant challenges to healthcare professionals' education and training. This study intended to measure nursing students' perceptions regarding their learning experiences on HAI prevention and control. In the first phase of the study, a cross-sectional and descriptive study with a convenience sample composed of undergradua...
The Role of Glucosinolates from Cruciferous Vegetables (Brassicaceae) in Gastro...
Melim, Catarina; Lauro, Maria R.; Pires, Isabel M.; Oliveira, Paulo J.; Cabral, CéliaThe gastrointestinal (GI) tract is composed of rapidly renewing cells, which increase the likelihood of cancer. Colorectal cancer is one of the most frequently diagnosed GI cancers and currently stands in second place regarding cancer-related mortality. Unfortunately, the treatment of GI is limited, and few developments have occurred in the field over the years. With this in mind, new therapeutic strategies inv...
Understanding dual career views of European university athletes: The more than ...
Capranica, Laura; Doupona, Mojca; Abelkalns, Ilvis; Bisenieks, Ugis; Sánchez-Pato, Antonio; Cánovas-Alvarez, Francisco José; Figueiredo, António JoséPrevious studies have found that student-athletes (S-As) have difficulties in achieving dual career (DC) success. However, no studies have analysed the opinion of the S-As on the functioning of DC with a qualitative methodology. The aim of the present work was to collect the opinions of elite university S-As in relation to DC policy adopted by their academic institutions in different European countries. In tota...
Anxiety levels moderate the association between visual acuity and health-relate...
Hugo Senra; Hernandez-Moreno, Laura; Moreno, Natacha; Macedo, António FilipeThe current study examines the potential moderating effect of depression and anxiety on the relationship between visual acuity and health-related quality of life in patients with chronic eye diseases. Of the 71 patients, 37 (52%) were female and 34 (48%) were male, age (mean ± SD) was 69 ± 12 years. A significant multivariate regression model was found for patients' health-related quality of life (EQ-5D-5L inde...
Chronic Nodular Prurigo: A European Cross-sectional Study of Patient Perspectiv...
Pereira, Manuel P.; Zeidler, Claudia; Wallengren, Joanna; Halvorsen, Jon Anders; Weisshaar, Elke; Garcovich, Simone; Misery, Laurent; Brenaut, EmilieChronic nodular prurigo is characterized by recalcitrant itch. Patient perspectives on therapeutic goals, satisfaction with therapy and efficacy of therapeutic regimens for this condition are unknown. This questionnaire study examined these issues in 406 patients with chronic nodular prurigo from 15 European dermatological centres. Improvements in itch, skin lesions and sleep were the most important goals. Emol...