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UAV-Based Structural Damage Mapping: A Review

Multicharged Phthalocyanines as Selective Ligands for G-Quadruplex DNA Structures

The stabilization of G-Quadruplex DNA structures by ligands is a promising strategy for telomerase inhibition in cancer therapy since this enzyme is responsible for the unlimited proliferation of cancer cells. To assess the potential of a compound as a telomerase inhibitor, selectivity for quadruplex over duplex DNA is a fundamental attribute, as the drug must be able to recognize quadruplex DNA in the presence...

Photocrosslinkable Nanofibrous Asymmetric Membrane Designed for Wound Dressing

Recently, the biomedical scientists who are working in the skin regeneration area have proposed asymmetric membranes as ideal wound dressings, since they are able to reproduce both layers of skin and improve the healing process as well as make it less painful. Herein, an electrospinning technique was used to produce new asymmetric membranes. The protective layer was composed of a blending solution between polyc...

Cytotoxicity profiling of deep eutectic solvents to human skin cells

The tailor-made character of deep eutectic solvents (DES) turns them very attractive to be used in several applications, including in health-related areas such as pharmaceutical, nutraceutical, and cosmetic industries. However, although DES has been touted as "green" solvents, several works proved that their potential toxicity should not be neglected. Using the premise of DES applicability in the cosmetic and p...

India in the Oil Palm Era: Describing India’s Dependence on Palm Oil, Recommend...

India is the largest consumer and importer of palm oil in the world. Its demand for palm oil is expected to double by 2030, which cannot be sustained just by increasing the import quantity, as it would be exporting its biodiversity issues to the supplying countries. We support the Government of India’s views to expand oil palm cultivation in India. However, an aggressive push toward domestic oil palm cultivatio...

Novel Highly Luminescent Amine-Functionalized Bridged Silsesquioxanes

Amine-functionalized bridged silsesquioxanes (BSs) were synthesized from bis[(3-trimethoxysilyl)propyl] amine via a solvent-mediated route. BS-1 and BS-2 were obtained at neutral pH with sub- and stoichiometric amounts of water, respectively, and high tetrahydrofuran content. BS-3 was prepared with hyperstoichiometric water concentration, high tetrahydrofuran content, and hydrochloric acid. BS-4 was synthesized...

Growth Cone Tctp Is Dynamically Regulated by Guidance Cues

Translationally controlled tumor protein (Tctp) contributes to retinal circuitry formation by promoting axon growth and guidance, but it remains unknown to what extent axonal Tctp specifically influences axon development programs. Various genome-wide profiling studies have ranked tctp transcripts among the most enriched in the axonal compartment of distinct neuronal populations, including embryonic retinal gang...

Study of methanogenic enrichment cultures of rock cores from the deep subsurfac...

Two deep boreholes were drilled at 320 and 620 meters below surface in the Iberian Pyritic Belt (IPB) at Peña de Hierro (Huelva, Southwestern Spain). Cores were sampled and used for the establishment of enrichment cultures with methanogenic activity. The cultivable diversity of these enrichments was accessed using different cultivation techniques and several isolates were recovered in pure culture from various ...

Doping β-TCP as a Strategy for Enhancing the Regenerative Potential of Composit...

The present work aims at evaluating the potential gains derived from partially replacing calcium in resorbable β-tricalcium phosphate (β-TCP) by two different molar percentages of strontium (5, 10) and zinc (1, 2), concomitantly with a fixed molar percentage (0.5) of manganese. Synthetic granular composite bone filling grafts consisting of doped β-TCP and an alkali-free bioactive glass were prepared and implant...

Microstructural Characterization of Dissimilar Titanium Alloys Joints Using Ni/...

This study demonstrates the potential of the use of Ni/Al nanolayers for joining dissimilar titanium alloys. For this purpose, a detailed microstructural characterization of the diffusion bonding interfaces of TiAl to Ti6Al4V, TiAl to TiNi and TiNi to Ti6Al4V was carried out. The nanolayers (alternated aluminum and nickel (Ni-7V wt.%) layers) were deposited onto the base material surfaces. Diffusion bonding was...