The credibility of online examinations in Higher Education is hardened by numerous factors and use-case scenarios. This paper reports on a longitudinal study, that spanned over eighteen months, in which various stakeholders from three European Higher Education Institutions (HEIs) participated, aiming to identify core threat scenarios experienced during online examinations, and to, accordingly, propose threat mo...
Skin tissue has a crucial role in protecting the human body from external harmful agents, preventing wounds that frequently demand proper healing approaches. The ethnobotanical knowledge of specific regions with further investigation on their medicinal plants has been paramount to create new and effective therapeutical agents, including for dermatological purposes. This review attempts, for the first time, to i...
Steroids constitute an important class of pharmacologically active molecules, playing key roles in human physiology. Within this group, 16E-arylideneandrostane derivatives have been reported as potent anti-cancer agents for the treatment of leukemia, breast and prostate cancers, and brain tumors. Additionally, 5α,6α-epoxycholesterol is an oxysterol with several biological activities, including regulation of cel...
We give positive answer to two conjectures posed by M. E. H Ismail in his monograph [Classical and quantum orthogonal polynomials in one variable, Cambridge University Press, Cambridge, 2005]. These results generalize the classical problems of Sonine and Hahn.
Lavandula pedunculata (Mill.) Cav., Mentha cervina L. and Thymus mastichina (L.) L. subsp. mastichina are representative species of the Côa Valley's flora, a Portuguese UNESCO World Heritage Site. L. pedunculata and T. mastichina are traditionally used to preserve olives and to aromatize bonfires on Saint John's Eve, while M. cervina is mainly used as a spice for river fish dishes. Despite their traditional use...
Energy efficiency is one of the most powerful strategies to mitigate the impacts of climate change by reducing energy demand, which in turn reduces the emissions of Green House Gases (GHG), as well as reducing the burden on the supply side renewable generation expansion. Because electric motors systems represent such a large share of the overall electricity consumption (over 50%), large savings potential could ...
The European baseline series was last updated in 2019. This article discusses the reasoning behind a further iteration of the series for 2023.
Introduction: The aim of this study was twofold: (1) to investigate the clinical impact of vision rehabilitation in patients with vision impairment and (2) to investigate the cost-effectiveness of a basic vision rehabilitation service in Portugal. Methods: The trial recruited patients diagnosed with age-related macular degeneration or diabetic retinopathy (DR) and visual acuity in the range 0.4–1.0logMAR in the...
Diamond-like-carbon “DLC” coatings can be deposited in many different ways, giving a large range of material properties suitable for many different types of applications. Hydrogen content significantly influences the mechanical properties and the tribological behavior of DLC coatings, but its determination requires techniques that are not available in many research centers. Thus, it is important to find alterna...
Neonatal hypoxic-ischemic encephalopathy (HIE) is one of the leading causes of death and long-term disability in the perinatal period. Currently, therapeutic hypothermia is the standard of care for this condition with modest efficacy and strict enrollment criteria. Therapy with umbilical cord blood cells (UCBC) has come forward as a strong candidate for the treatment of neonatal HIE, but no preclinical studies ...