3125265 documents found, page 312293 of 312527

Preventing regrettable substitutions

Bisphenol A (BPA) alternatives are increasingly used in the manufacture of industrial and consumer products, following regulatory restrictions on BPA. However, insufficient safety data on these substitutes raise concern as regards potential regrettable substitutions. Under the EU Partnership for the Assessment of Risks from Chemicals (PARC), Work Package 5 (WP5) addresses this challenge by applying a human-rele...

An AI-Enhanced Bibliometric Analysis of Customer Feedback and Hotel Performance...

In the digital era, customer feedback has evolved into a strategic asset influencing hotel performance, competitiveness, and investment decisions. This study reviews the relationship between online reviews and key performance indicators (KPIs) in the hospitality sector and proposes an AI-enhanced literature review framework. By integrating bibliometric analysis, Natural Language Processing (NLP), and Large Lang...

The value of trademarks

We create a new measure of the value of an important, but previously understudied, intangible asset —trademarks. We quantify the stock market reaction to the publication of individual trademarks manually matched to U.S. publicly traded firms. We find that trademarks are used ubiquitously and possess substantial value: the median trademark is worth $20 million. Firms that obtain new trademarks subsequently launc...

Nutritional Profile of Children, Adolescents, and Women Living in Areas Potenti...

BACKGROUND: The global nutrition crisis continues to disproportionately affect vulnerable populations' health in regions where artisanal mining is high. OBJECTIVE: This study assessed the nutritional status of children, adolescents, and women living in the Revuè sub-basin, who are potentially exposed to heavy metal contaminants. METHODS: An observational and cross-sectional design was used to combine anthropome...

Seeing Intracranial in-Stent Restenosis Before it Happens

Clinical predictors of response to methotrexate in patients with rheumatoid art...

Background: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint inflammation, structural damage, and disability. Methotrexate (MTX) is the first-line treatment; however, up to one-third of patients exhibit an inadequate response. This systematic review aimed to identify clinical, serological, genetic, pharmacogenomic, and treatment-related predictors of MTX response in RA. Methods: ...

How do renewable energy communities impact household energy consumption?

Renewable Energy Communities (RECs) are increasingly recognised as key instruments for a just energy transition. Yet evidence on their impact on households’ energy behaviour remains limited. This study focuses on the Agra do Amial REC, located in a deprived neighbourhood in Porto, Portugal’s second largest city, and assesses its impact on electricity consumption and expenditures. Using high-frequency (hourly/da...

Tissue-specific expression and regulation of congenital disorders of glycosylat...

Congenital disorders of glycosylation (CDGs) are rare metabolic diseases characterized by clinical heterogeneity, yet the molecular basis for their tissue-specific manifestations remains poorly understood. Because affected tissues are rarely accessible for biopsy, the baseline transcriptional and regulatory landscape of CDG-causative genes in healthy human tissues offers a valuable, complementary perspective on...

NextGenerationEU landing

In response to the COVID-19 crisis, the European Union introduced NextGenerationEU, its largest stimulus package to date. We focus on Italy, the program's largest beneficiary, and analyse the territorial distribution of funds. Although centrally coordinated, most expenditures were awarded through calls and implemented by local governments. Using a sample of approximately 4500 Italian municipalities for which ad...

Mapping inequalities in rheumatology care in Europe

Objectives: To describe inequalities in health indicators relevant for quality of care to people with rheumatic and musculoskeletal diseases (RMDs) across Europe by comparing RMD health system indicators across European Alliance of Associations for Rheumatology (EULAR) member countries. Methods: RheumaFacts is an EULAR initiative to improve the quality of care across Europe by monitoring access to and outcomes ...