3125393 documents found, page 312335 of 312540
Alcohol and liver damage.
Sherlock, SheilaThe association of alcohol with cirrhosis was recognised by Matthew Baillie in 1793 and later by Addison. In Western countries the incidence of cirrhosis can be directly related to the quantity of alcohol consumed. In France, between - 1941 and 1947, rationing of wine from five to one litre per week led to an 80% reduction in mortality from cirrhosis. Cirrhosis is on the increase. In the U.S.A. it is the fourth...
Hepatic surgery.
Blumgart, L. H.; Wood, C. B.The ability of the human liver to undergo regenerative hyperplasia after resection has been recognised for many centuries and reference is found to it in ancient mythology. It is this amazing potential for the regrowth that allows resection of large portions of liver substance. In recent years, detailed anatomical studies have defined the segments and lobes of the liver and provide the Surgeon with the necessar...
Disturbances of metabolic homeostasis is liver disease.
Alberti, K. G. M. M.; Johnston, D. G.; Piniewska-Hulas, M.; Whittaker, J.The liver occupies a major role in metabolic homeostasis with important functions in carbohydrate, fat and protein metabolism. Abnormalities in glucose homeostasis are common in all forms of liver disease although fasting hypoglycaemia is surprisingly rare. Blood concentrations of the gluconeogenic precursors, lactate and pyruvate, are raised in liver disease, particularly hepatic cirrhosis, although glucogenic...
Autoantibodies in alcoholic liver cirrhosis in Portugal.
Monteiro, Estela; Correia, J. PintoSera from 62 patients with alcoholic liver cirrhosis were tested for the presence of organ specific and non organ specific autoantibodies and compared with a healthy group as a control population. SMA was found in an overall percentage of 26% (30% among females and 23% among males). The titers were under 1/80. ANA was found in an overall percentage of 8% with low titers. The prevalence of SMA and ANA in the alc...
Chronic hepatitis.
Wright, RalphThe term chronic hepatitis is used to include prolonged inflammation of the liver following an attack of acute viral hepatitis, either icteric or anicteric, or chronic active hepatitis, of unknown aetiology. We accept the Fogarty proceedings definition of chronic hepatitis as inflammation of the liver for six months or more, although the duration of the biochemical or histological abnormalities before the term ...
Immunology of liver disease.
Triger, David R.There appears to be strong evidence to suggest that the liver plays an important role in the normally functioning immune system and in disorders involving damage to the liver disturbances in the immunological parameters are frequently found. In the light of our current knowledge, however, it is not clear whether these disturbances occur secondary to this liver damage or whether some or all of them provide the i...
Alpha-1-antitrypsin deficiency and liver disease.
Millward-Sadler, G. H.In this review article only the liver disease associated with aipha-1-antitrypsin deficiency will be considered. For the well recognised association with lung disease the review by Mittman is recommended.
The haematology of liver disease.
Chisholm, MoragIn the early weeks of foetal development the liver is the main site of production of red cells, white cells and platelets. With increasing maturity of the foetus, this function is taken over by the bone marrow, but the liver still retains a potential for haemopoiesis even in adult life. After birth the major active role of the liver in relation to the blood is in the destruction and removal of red cells, and th...
Hepatic amebiasis: experience in the therapy of 56 cases.
Cruz, Ireneu; Carneiro Chaves, F. J. Z.The results of therapy in 56 consecutive cases of hepatic amebiasis are reviewed. In retrospect, the results in patients receiving metronidazole alone, dehydroemetine combined with chloroquine, and dehydroemetine combined with chloroquine and metronidazole were compared. No deaths occured. Our results confirm the great efficacy of metronidazole alone. The response to treatment was similar in patients receiving ...
Biochemical changes in cholestasis. Peripheral impact.
Martínez Fernández, A.La función biliar consiste en ia secrecion y excreción de bilis y otros elementos por las vias biliares ai intestino.