Clinical Practice Guidelines are instruments to support decision to improve the quality of clinical care. An expert group from McMaster University (Canada) has developed - from high-quality literature sources – a guidance on the practical steps for their development, dissemination, implementation and evaluation. This is the 1st time anyone seeks to bring together in one document all information regarding the Cl...
Introduction: Allergic contact dermatitis, along with irritant contact dermatitis and immediate contact reactions, contact urticarial, are the most frequent dermatological occupational disease, but seldom reported to the National authorities.Material and Methods: We performed a 3-year retrospective study at the allergology section in the Dermatology Clinic of the University Hospital of Coimbra to evaluate the m...
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Introduction: Diffuse large B-cell lymphoma can be cured in 60% – 70% of patients. Autologous stem cell transplantation is the standard treatment for relapsed disease. This high-intensity treatment after first complete remission in patients with high International Prognostic Index remains controversial and was performed in our department during some years. Material and Methods: Retrospective study, review of cl...
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Introduction: Though typically found in adolescents, acne frequently affects the adult population. In Portugal, no representative studies about acne prevalence in greater populational areas are known. This study had the following objectives: calculate acne prevalence in primary healthcare patients; its characteristics, including risk factors for onset and worsening; collect information concerning selfmedication...
Keywords: Lumbar Vertebrae/abnormalities; Lumbar Vertebrae/radiography.; Palavras-chave: Vértebras Lombares/anomalias congénitas; Vértebras Lombares/radiografia.
Isolated acute abdominal aortic dissection is a relatively rare event. Its natural history is not fully understood and its optimal treatment is not established. Open surgery represents the most described treatment but endovascular intervention has had increasing application. Isolated chronic abdominal aortic dissection is even less described in the literature. We describe three patients with isolated chronic a...
Introduction: Helicobacter pylori infection is very prevalent worldwide and is associated with the progression of the gastriccarcinogenesis cascade, being one of the main risk factors for the development of gastric carcinoma. Several factors are determinant for the infection and for the development of gastric disease, including environmental factors, host genetic factors and virulence factors of the bacteria.Ma...
The Portuguese health system has considerable strengths and an impressive track record of success, but is facing severe challenges due to increasing demand and restricted funding. Its continuing success will depend on how citizens and clinicians respond to these challenges as well as on a clear vision for the future and good collective leadership from health professionals, politicians and others in wider societ...