3125560 documents found, page 312534 of 312556
Safety Alerts: An Observational Study in Portugal
Soares, Sara; Roque, Fátima; Rodrigues, António; Figueiras, Adolfo; Herdeiro, MariaPurpose: The information that is available when marketing authorizations are approved is limited. Pharmacovigilance has an important role during the postauthorization period, and alerts published by national authorities allow health care professionals to be informed about new data on safety profiles. This study therefore sought to analyze all safety alerts published by the Portuguese National Authority of Medic...
Assessment of Potentially Inappropriate Medications Using the EU (7)-PIM List, ...
Plácido, Ana; Aguiar, Ana; Piñeiro-Lamas, María; Varallo, Fabiana; Figueiras, Adolfo; Herdeiro, Maria; Roque, FátimaAbstract: Prescription of potentially inappropriate medication (PIM) in older adults is associated with poor clinical outcomes. The EU (7)-PIM list was created for the European market to improve pharmacotherapy in older adults. Purpose: This work aims to characterize the medication profile and assess the presence of PIM, using the EU (7)-PIM list in older adults' residents at nursing homes. Methods: Retrospecti...
Decreasing antibiotic use through a joint intervention targeting physicians and...
Roque, Fátima; Rodrigues, António; Breitenfeld, Luiza; Piñeiro-Lamas, Maria; Figueiras, Adolfo; Herdeiro, MariaAim: To decrease population antibiotic use through an educational intervention targeting primary care physicians' and community pharmacists' attitudes and knowledge. Methods: We designed a pragmatic cluster-randomized trial covering all National Health System primary care physicians and all community pharmacists' in a region in the north of Portugal. The study protocol was registered on ClinicalTrials.gov (iden...
Daily Medication Management and Adherence in the Polymedicated Elderly: A Cross...
Gomes, Daniel; Plácido, Ana; Mó, Rita; Simões, João; Amaral, Odete; Fernandes, Isabel; Lima, Fátima; Morgado, Manuel; Figueiras, Adolfo; Herdeiro, MariaThe presence of age-related comorbidities prone elderly patients to the phenomenon of polypharmacy and consequently to a higher risk of nonadherence. Thus, this paper aims to characterize the medication consumption profile and explore the relationship of beliefs and daily medication management on medication adherence by home-dwelling polymedicated elderly people. A questionnaire on adherence, managing, and beli...
Oromucosal Alginate Films with Zein Nanoparticles as a Novel Delivery System fo...
Rodrigues, Daniela A; Miguel, Sónia P; Loureiro, Jorge; Ribeiro, Maximiano; Roque, Fátima; Coutinho, PaulaDigoxin is a hydrophobic drug used for the treatment of heart failure that possesses a narrow therapeutic index, which raises safety concerns for toxicity. This is of utmost relevance in specific populations, such as the elderly. This study aimed to demonstrate the potential of the sodium alginate films as buccal drug delivery system containing zein nanoparticles incorporated with digoxin to reduce the number o...
Clinical pharmacists interventions in the management of type 2 diabetes mellitu...
Pousinho, Sarah; Morgado, Manuel; Plácido, Ana; Roque, Fátima; Falcão, Amílcar; Alves, GilbertoBackground: Type 2 diabetes mellitus is a chronic disease that is reaching epidemic proportions worldwide. It is imperative to adopt an integrated strategy, which involves a close collaboration between the patient and a multidisciplinary team of which pharmacists should be integral elements. Objective: This work aims to identify and summarize the main effects of interventions carried out by clinical pharmacists...
Implementação de uma comissão de trabalhadores na ULS Guarda, EPE
Andrade, Jó E EA participação dos trabalhadores nos processos de gestão das empresas é um conceito que surgiu em meados da década de 1920, decorrente do próprio processo de organização do trabalho. Apesar de ser um direito consagrado no Artigo 54.º da Constituição da República Portuguesa, são poucas as entidades públicas ou privadas em que existe uma participação efetiva dos trabalhadores na gestão. Com este projeto, elaborad...
Proposta de Sistema de Gestão de Responsabilidade Social no Laboratório de Saúd...
Pacheco, Nzola A C GAs organizações têm vindo a assumir compromissos com a responsabilidade social (RS), ao valorizar o desenvolvimento de práticas éticas, sociais e ambientalmente responsáveis na definição das suas estratégias e atividades. O conceito de RS encontra-se relacionado com a ideia de desenvolvimento sustentável e a adoção, de forma voluntária, de práticas socialmente responsáveis por parte das organizações, promovendo...
A Mobile App to Support Clinical Diagnosis of Upper Respiratory Problems (eHeal...
Moura, Joana; Almeida, Ana; Roque, Fátima; Figueiras, Adolfo; Herdeiro, MariaBackground: The misuse of antibiotics is a global public health issue that fosters bacterial resistance and jeopardizes generational health. The development of validated tools such as web-based courses and mobile apps to enhance clinical decisions in upper respiratory infections is of great importance in reducing the incorrect use of antibiotics in these situations. Objective: The aim of this study was to desig...
Prescription of anxiolytics, sedatives, hypnotics and antidepressants in outpat...
Estrela, Marta; Silva, Tânia; Gomes, Eva; Piñeiro, Maria; Figueiras, Adolfo; Roque, Fátima; Herdeiro, MariaBackground: The COVID-19 pandemic has had a significant impact on the population's mental health. However, its impact on the consumption of anxiolytics, sedatives, hypnotics and antidepressants remains to be evaluated. Hence, this article aims to assess the prescription trends of these drugs in Portugal, from January 2018 to March 2021, while critically examining whether the COVID-19 pandemic had an impact on t...