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Experiments on computer assisted optimization of the escherichia coli fermentation process using Optferm

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Detalhes bibliográficos
Resumo:We used the software Optferm to model and optimize the bioprocess of escherichia coli fermentation, simulating the conditions of a fed-batch bioreactor. The results, obtained by employing different AI approaches, provided useful orientation for nutrient feed strategies for increased productivity. In conclusion, we believe in silico tools can perform a rapid and valid optimization of bioprocesses avoiding expensive experiments.
Autores principais:Teixeira, Tânia
Outros Autores:Deusdado, Sérgio
Assunto:Bioprocesses optimization Bioprocesses modeling
Ano:2011
País:Portugal
Tipo de documento:comunicação em conferência
Tipo de acesso:acesso aberto
Instituição associada:Instituto Politécnico de Bragança
Idioma:inglês
Origem:Biblioteca Digital do IPB
Descrição
Resumo:We used the software Optferm to model and optimize the bioprocess of escherichia coli fermentation, simulating the conditions of a fed-batch bioreactor. The results, obtained by employing different AI approaches, provided useful orientation for nutrient feed strategies for increased productivity. In conclusion, we believe in silico tools can perform a rapid and valid optimization of bioprocesses avoiding expensive experiments.