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Minimisation of acquisition time in a TOF PET/CT scanner without compromising image quality

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Resumo:Significant improvements have been made in Positron Emission Tomography (PET) to enhance the image quality, namely, the development of time-of-flight (TOF) technology. This technique is useful to localize the emission point of the beta plus-emitter (β+) radiopharmaceutical inside the body, allowing better lesion contrast and leading to a short scan time. The main goal of this study is to investigate the shortest acquisition time without compromising the image quality in both a NEMA body phantom and patients, using a TOF PET/Computed Tomography (PET/CT) scanner and the radionuclide Gallium-68 (68Ga). Image quality parameters and quantification in terms of standardized uptake value (SUV) were acquired. A time between 45 and 60 s per bed position is proposed for future clinical practices.
Autores principais:Oliveira, Joana
Outros Autores:Parafita, Rui; Branco, Susana
Assunto:PET/CT TOF 68Ga Acquisition time Image quality
Ano:2018
País:Portugal
Tipo de documento:capítulo de livro
Tipo de acesso:acesso restrito
Instituição associada:Instituto Politécnico de Lisboa
Idioma:inglês
Origem:Repositório Científico do Instituto Politécnico de Lisboa
Descrição
Resumo:Significant improvements have been made in Positron Emission Tomography (PET) to enhance the image quality, namely, the development of time-of-flight (TOF) technology. This technique is useful to localize the emission point of the beta plus-emitter (β+) radiopharmaceutical inside the body, allowing better lesion contrast and leading to a short scan time. The main goal of this study is to investigate the shortest acquisition time without compromising the image quality in both a NEMA body phantom and patients, using a TOF PET/Computed Tomography (PET/CT) scanner and the radionuclide Gallium-68 (68Ga). Image quality parameters and quantification in terms of standardized uptake value (SUV) were acquired. A time between 45 and 60 s per bed position is proposed for future clinical practices.