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Synthesis of glycoconjugates containing a 1,2,3-triazole unit

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Detalhes bibliográficos
Resumo:The preparation of several alkynyl esters, derived from amino acids, coumarins and an alkynyl derivative of acetylated D-glucose is described. Eight new glycoconjugates containing the 1,2,3-triazole unit were obtained, by a click approach from the above referred alkynyl derivatives with tetracetyl-beta-D-glucosylazide, prepared in situ from alpha-acetobromoglucose.
Autores principais:Cunha, Sandra Raquel Leite
Outros Autores:Pereira, S.; Malheiro, M.; Rodrigues, Lígia M.; Campos, Ana M. F. Oliveira; Esteves, Ana Paula
Assunto:Glycoconjugates Click chemistry Triazole Alkynyl esters
Ano:2013
País:Portugal
Tipo de documento:outro
Tipo de acesso:acesso aberto
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
Descrição
Resumo:The preparation of several alkynyl esters, derived from amino acids, coumarins and an alkynyl derivative of acetylated D-glucose is described. Eight new glycoconjugates containing the 1,2,3-triazole unit were obtained, by a click approach from the above referred alkynyl derivatives with tetracetyl-beta-D-glucosylazide, prepared in situ from alpha-acetobromoglucose.