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Hypertension: protective effects of physical exercise on cognition function, arterial function and brain health

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Resumo:Systemic Arterial Hypertension (SAH) is a chronic condition that requires clinical treatment and is associated with increased risk of cognitive impairment and dementia. Therefore, strategies with fewer side effects and less invasive procedures are required. Evidence supports that Physical Exercise (PE) has antihypertensive effects and has proven to be an efficient and complementary tool for managing hypertension, reducing cardiovascular disease risk factors, and improving cerebral perfusion in the majority of healthy populations. Much of this cardiovascular-protective effect of PE is probably due to pluripotent effects on the vasculature, including regulation of vascular tone, energy metabolism, microvascular recruitment, and endothelial function (reducing oxidative stress and preserving NO availability). These factors are speculated to work synergistically, thereby reducing systolic and diastolic blood pressure and are directly related to improved cerebrovascular function. However, few studies have specifically examined the potential positive effects of PE on the brain in hypertensive individuals. In this brief review, we discuss the potential effect of different PE modalities (aerobic, resistance, and combined) that may act as an effective preventive or therapeutic strategy for reducing blood pressure in hypertensives and, consequently, mitigate the association between hypertension, cognitive impairment and risk of dementia.
Autores principais:Pedralli, Marinei Lopes
Outros Autores:Barbosa, Eduardo; Cunha, Pedro Miguel Guimarães Marques
Assunto:Hypertension Cognition Exercise Vascular health Rehabilitation
Ano:2019
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
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author Pedralli, Marinei Lopes
author2 Barbosa, Eduardo
Cunha, Pedro Miguel Guimarães Marques
author2_role author
author
author_facet Pedralli, Marinei Lopes
Barbosa, Eduardo
Cunha, Pedro Miguel Guimarães Marques
author_role author
contributor_name_str_mv RepositóriUM - Universidade do Minho
country_str PT
creators_json_txt [{\"Person.name\":\"Pedralli, Marinei Lopes\"},{\"Person.name\":\"Barbosa, Eduardo\"},{\"Person.name\":\"Cunha, Pedro Miguel Guimarães Marques\"}]
datacite.contributors.contributor.contributorName.fl_str_mv RepositóriUM - Universidade do Minho
datacite.creators.creator.creatorName.fl_str_mv Pedralli, Marinei Lopes
Barbosa, Eduardo
Cunha, Pedro Miguel Guimarães Marques
datacite.date.Accepted.fl_str_mv 2019-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2020-10-02T14:35:55Z
datacite.date.embargoed.fl_str_mv 2020-10-02T14:35:55Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Hypertension
Cognition
Exercise
Vascular health
Rehabilitation
datacite.titles.title.fl_str_mv Hypertension: protective effects of physical exercise on cognition function, arterial function and brain health
dc.contributor.none.fl_str_mv RepositóriUM - Universidade do Minho
dc.creator.none.fl_str_mv Pedralli, Marinei Lopes
Barbosa, Eduardo
Cunha, Pedro Miguel Guimarães Marques
dc.date.Accepted.fl_str_mv 2019-01-01T00:00:00Z
dc.date.available.fl_str_mv 2020-10-02T14:35:55Z
dc.date.embargoed.fl_str_mv 2020-10-02T14:35:55Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv https://hdl.handle.net/1822/67261
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Atlantis Press
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv Hypertension
Cognition
Exercise
Vascular health
Rehabilitation
dc.title.fl_str_mv Hypertension: protective effects of physical exercise on cognition function, arterial function and brain health
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description Systemic Arterial Hypertension (SAH) is a chronic condition that requires clinical treatment and is associated with increased risk of cognitive impairment and dementia. Therefore, strategies with fewer side effects and less invasive procedures are required. Evidence supports that Physical Exercise (PE) has antihypertensive effects and has proven to be an efficient and complementary tool for managing hypertension, reducing cardiovascular disease risk factors, and improving cerebral perfusion in the majority of healthy populations. Much of this cardiovascular-protective effect of PE is probably due to pluripotent effects on the vasculature, including regulation of vascular tone, energy metabolism, microvascular recruitment, and endothelial function (reducing oxidative stress and preserving NO availability). These factors are speculated to work synergistically, thereby reducing systolic and diastolic blood pressure and are directly related to improved cerebrovascular function. However, few studies have specifically examined the potential positive effects of PE on the brain in hypertensive individuals. In this brief review, we discuss the potential effect of different PE modalities (aerobic, resistance, and combined) that may act as an effective preventive or therapeutic strategy for reducing blood pressure in hypertensives and, consequently, mitigate the association between hypertension, cognitive impairment and risk of dementia.
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eu_rights_str_mv openAccess
format article
fulltext.url.fl_str_mv https://repositorium.uminho.pt/bitstreams/56c7919f-39f3-463e-acb3-00af82b4f5e9/download
id rum_2fa4b17ba9322aed2ef69cbd97ce9f6b
identifier.url.fl_str_mv https://hdl.handle.net/1822/67261
instacron_str repositorium
institution Universidade do Minho
instname_str Universidade do Minho
language eng
network_acronym_str rum
network_name_str RepositóriUM - Universidade do Minho
oai_identifier_str oai:repositorium.uminho.pt:1822/67261
organization_str_mv urn:organizationAcronym:repositorium
person_str_mv Pedralli, Marinei Lopes
Barbosa, Eduardo
Cunha, Pedro Miguel Guimarães Marques
publishDate 2019
publisher.none.fl_str_mv Atlantis Press
reponame_str RepositóriUM - Universidade do Minho
repository_id_str urn:repositoryAcronym:rum
service_str_mv urn:repositoryAcronym:rum
spelling engAtlantis PressporSystemic Arterial Hypertension (SAH) is a chronic condition that requires clinical treatment and is associated with increased risk of cognitive impairment and dementia. Therefore, strategies with fewer side effects and less invasive procedures are required. Evidence supports that Physical Exercise (PE) has antihypertensive effects and has proven to be an efficient and complementary tool for managing hypertension, reducing cardiovascular disease risk factors, and improving cerebral perfusion in the majority of healthy populations. Much of this cardiovascular-protective effect of PE is probably due to pluripotent effects on the vasculature, including regulation of vascular tone, energy metabolism, microvascular recruitment, and endothelial function (reducing oxidative stress and preserving NO availability). These factors are speculated to work synergistically, thereby reducing systolic and diastolic blood pressure and are directly related to improved cerebrovascular function. However, few studies have specifically examined the potential positive effects of PE on the brain in hypertensive individuals. In this brief review, we discuss the potential effect of different PE modalities (aerobic, resistance, and combined) that may act as an effective preventive or therapeutic strategy for reducing blood pressure in hypertensives and, consequently, mitigate the association between hypertension, cognitive impairment and risk of dementia.application/pdfporHypertension: protective effects of physical exercise on cognition function, arterial function and brain healthPedralli, Marinei LopesBarbosa, EduardoCunha, Pedro Miguel Guimarães MarquesHostingInstitutionOrganizationalRepositóriUM - Universidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptISSNIsPartOf1872-9312EISSNIsPartOf1876-4401DOIIsPartOf10.2991/artres.k.191203.0032020-10-02T14:35:55Z20192019-01-01T00:00:00ZHandlehttps://hdl.handle.net/1822/67261http://purl.org/coar/access_right/c_abf2open accessHypertensionCognitionExerciseVascular healthRehabilitation322023 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://repositorium.uminho.pt/bitstreams/56c7919f-39f3-463e-acb3-00af82b4f5e9/download
spellingShingle Hypertension: protective effects of physical exercise on cognition function, arterial function and brain health
Pedralli, Marinei Lopes
Hypertension
Cognition
Exercise
Vascular health
Rehabilitation
status SINGLETON
subject.fl_str_mv Hypertension
Cognition
Exercise
Vascular health
Rehabilitation
title Hypertension: protective effects of physical exercise on cognition function, arterial function and brain health
title_full Hypertension: protective effects of physical exercise on cognition function, arterial function and brain health
title_fullStr Hypertension: protective effects of physical exercise on cognition function, arterial function and brain health
title_full_unstemmed Hypertension: protective effects of physical exercise on cognition function, arterial function and brain health
title_short Hypertension: protective effects of physical exercise on cognition function, arterial function and brain health
title_sort Hypertension: protective effects of physical exercise on cognition function, arterial function and brain health
topic Hypertension
Cognition
Exercise
Vascular health
Rehabilitation
topic_facet Hypertension
Cognition
Exercise
Vascular health
Rehabilitation
url https://hdl.handle.net/1822/67261
visible 1