Publication

Calcium-phosphate derived from mineralized algae for bone tissue engineering applications

Bibliographic Details
Summary:	In this work, several routes are described towards obtaining pure inorganic phases derived from Coralline officinallis red algae. The scanning electron microscopy studies have shown that it becomes possible not only to eliminate the undesired organic phase, but also to preserve or tailor the red algae typical microporosity. X-ray diffraction analysis was used to investigate the phase content of the red algae before and after performing the different treatment routes. Hydroxyapatite nanocrystallites were obtained after converting the coralline calcium carbonate skeleton by means of combining thermal and chemical routes. These results were confirmed by Fourier transform infra-red spectroscopic analysis. The processing routes herein described are very promising in order to design bioceramics of algae origin that might find useful applications as bone fillers and tissue engineering scaffolds.
Main Authors:	Oliveira, Joaquim M.
Other Authors:	Grech, Jessica M. R.; Leonor, I. B.; Mano, J. F.; Reis, R. L.
Subject:	Calcium-phosphate Coralline officinallis Hydroxyapatite Mineralized red algae Bone tissue engineering
Year:	2007
Country:	Portugal
Document type:	article
Access type:	open access
Associated institution:	Universidade do Minho
Language:	English
Origin:	RepositóriUM - Universidade do Minho

Description
Summary:	In this work, several routes are described towards obtaining pure inorganic phases derived from Coralline officinallis red algae. The scanning electron microscopy studies have shown that it becomes possible not only to eliminate the undesired organic phase, but also to preserve or tailor the red algae typical microporosity. X-ray diffraction analysis was used to investigate the phase content of the red algae before and after performing the different treatment routes. Hydroxyapatite nanocrystallites were obtained after converting the coralline calcium carbonate skeleton by means of combining thermal and chemical routes. These results were confirmed by Fourier transform infra-red spectroscopic analysis. The processing routes herein described are very promising in order to design bioceramics of algae origin that might find useful applications as bone fillers and tissue engineering scaffolds.