Publicação
Suspected blood indicator in capsule endoscopy: a valuable tool for gastrointestinal bleeding diagnosis
| Resumo: | Small bowel bleeding is a leading indication for small bowel capsule endoscopy. The Suspected Blood Indicator (SBI) is a software feature directed to automatically detect bleeding lesions during small bowel capsule endoscopy. Objective – We aimed to assess SBI diagnostic accuracy for small bowel haemorrhage or potentially bleeding lesions during small bowel capsule endoscopy for small bowel bleeding. Methods – Single-centre retrospective study including 281 consecutive small bowel capsule endoscopy performed for small bowel bleeding during 6 years. The investigators marked lesions with high bleeding potential (P2), such as angioectasias, ulcers and tumours, as well as active bleeding during regular small bowel capsule endoscopy viewing with PillCam SB2®. All small bowel capsule endoscopy were independently reviewed by another central reader using SBI. Results – Among the 281 patients, 29 (10.3%) presented with active haemorrhage while 81 (28.9%) presented with a P2 lesion. The most frequently observed P2 lesions were angioectasias (52), ulcers (15), polyps (7) and ulcerated neoplasias (7). SBI showed a 96.6% (28/29) sensitivity for active small bowel bleeding, with a 97.7% negative predictive value. Regarding P2 lesions, the SBI displayed an overall sensitivity of 39.5%, being highest for ulcerated neoplasias (100%), but significantly lower for angioectasias (38.5%) or ulcers (20.0%). Conclusion – Although SBI sensitivity for the automatic detection of potentially bleeding lesions was low, it effectively detected active small bowel bleeding with very high sensitivity and negative predictive value. |
|---|---|
| Autores principais: | Boal Carvalho, Pedro |
| Outros Autores: | Magalhães, Joana; Dias DE Castro, Francisca; Monteiro, Sara; Rosa, Bruno; Moreira, Maria João; Cotter, José Almeida Berkeley |
| Assunto: | Adult Endoscopy, Gastrointestinal Female Gastrointestinal Hemorrhage Humans Male Predictive Value of Tests Retrospective Studies Sensitivity and Specificity Capsule Endoscopy Small intestine |
| Ano: | 2017 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| _version_ | 1867438606305460224 |
|---|---|
| author | Boal Carvalho, Pedro |
| author2 | Magalhães, Joana Dias DE Castro, Francisca Monteiro, Sara Rosa, Bruno Moreira, Maria João Cotter, José Almeida Berkeley |
| author2_role | author author author author author author |
| author_facet | Boal Carvalho, Pedro Magalhães, Joana Dias DE Castro, Francisca Monteiro, Sara Rosa, Bruno Moreira, Maria João Cotter, José Almeida Berkeley |
| author_role | author |
| contributor_name_str_mv | RepositóriUM - Universidade do Minho |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Boal Carvalho, Pedro\"},{\"Person.name\":\"Magalhães, Joana\"},{\"Person.name\":\"Dias DE Castro, Francisca\"},{\"Person.name\":\"Monteiro, Sara\"},{\"Person.name\":\"Rosa, Bruno\"},{\"Person.name\":\"Moreira, Maria João\"},{\"Person.name\":\"Cotter, José Almeida Berkeley\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | RepositóriUM - Universidade do Minho |
| datacite.creators.creator.creatorName.fl_str_mv | Boal Carvalho, Pedro Magalhães, Joana Dias DE Castro, Francisca Monteiro, Sara Rosa, Bruno Moreira, Maria João Cotter, José Almeida Berkeley |
| datacite.date.Accepted.fl_str_mv | 2017-01-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2019-01-15T17:34:25Z |
| datacite.date.embargoed.fl_str_mv | 2019-01-15T17:34:25Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Adult Endoscopy, Gastrointestinal Female Gastrointestinal Hemorrhage Humans Male Predictive Value of Tests Retrospective Studies Sensitivity and Specificity Capsule Endoscopy Small intestine |
| datacite.titles.title.fl_str_mv | Suspected blood indicator in capsule endoscopy: a valuable tool for gastrointestinal bleeding diagnosis "Suspected Blood Indicator" na enteroscopia por cápsula: uma ferramenta útil no diagnóstico de hemorragia gastrointestinal |
| dc.contributor.none.fl_str_mv | RepositóriUM - Universidade do Minho |
| dc.creator.none.fl_str_mv | Boal Carvalho, Pedro Magalhães, Joana Dias DE Castro, Francisca Monteiro, Sara Rosa, Bruno Moreira, Maria João Cotter, José Almeida Berkeley |
| dc.date.Accepted.fl_str_mv | 2017-01-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2019-01-15T17:34:25Z |
| dc.date.embargoed.fl_str_mv | 2019-01-15T17:34:25Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | https://hdl.handle.net/1822/58242 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE) |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | Adult Endoscopy, Gastrointestinal Female Gastrointestinal Hemorrhage Humans Male Predictive Value of Tests Retrospective Studies Sensitivity and Specificity Capsule Endoscopy Small intestine |
| dc.title.fl_str_mv | Suspected blood indicator in capsule endoscopy: a valuable tool for gastrointestinal bleeding diagnosis "Suspected Blood Indicator" na enteroscopia por cápsula: uma ferramenta útil no diagnóstico de hemorragia gastrointestinal |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Small bowel bleeding is a leading indication for small bowel capsule endoscopy. The Suspected Blood Indicator (SBI) is a software feature directed to automatically detect bleeding lesions during small bowel capsule endoscopy. Objective – We aimed to assess SBI diagnostic accuracy for small bowel haemorrhage or potentially bleeding lesions during small bowel capsule endoscopy for small bowel bleeding. Methods – Single-centre retrospective study including 281 consecutive small bowel capsule endoscopy performed for small bowel bleeding during 6 years. The investigators marked lesions with high bleeding potential (P2), such as angioectasias, ulcers and tumours, as well as active bleeding during regular small bowel capsule endoscopy viewing with PillCam SB2®. All small bowel capsule endoscopy were independently reviewed by another central reader using SBI. Results – Among the 281 patients, 29 (10.3%) presented with active haemorrhage while 81 (28.9%) presented with a P2 lesion. The most frequently observed P2 lesions were angioectasias (52), ulcers (15), polyps (7) and ulcerated neoplasias (7). SBI showed a 96.6% (28/29) sensitivity for active small bowel bleeding, with a 97.7% negative predictive value. Regarding P2 lesions, the SBI displayed an overall sensitivity of 39.5%, being highest for ulcerated neoplasias (100%), but significantly lower for angioectasias (38.5%) or ulcers (20.0%). Conclusion – Although SBI sensitivity for the automatic detection of potentially bleeding lesions was low, it effectively detected active small bowel bleeding with very high sensitivity and negative predictive value. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| fulltext.url.fl_str_mv | https://repositorium.uminho.pt/bitstreams/525f6057-7118-4ac8-bc54-112d5b8bba49/download |
| id | rum_528b77e2a427c2d7d5d03c5bbbc8f3b8 |
| identifier.url.fl_str_mv | https://hdl.handle.net/1822/58242 |
| instacron_str | repositorium |
| institution | Universidade do Minho |
| instname_str | Universidade do Minho |
| language | eng |
| network_acronym_str | rum |
| network_name_str | RepositóriUM - Universidade do Minho |
| oai_identifier_str | oai:repositorium.uminho.pt:1822/58242 |
| organization_str_mv | urn:organizationAcronym:repositorium |
| person_str_mv | Boal Carvalho, Pedro Magalhães, Joana Dias DE Castro, Francisca Monteiro, Sara Rosa, Bruno Moreira, Maria João Cotter, José Almeida Berkeley |
| publishDate | 2017 |
| publisher.none.fl_str_mv | Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE) |
| reponame_str | RepositóriUM - Universidade do Minho |
| repository_id_str | urn:repositoryAcronym:rum |
| service_str_mv | urn:repositoryAcronym:rum |
| spelling | engInstituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE)engSmall bowel bleeding is a leading indication for small bowel capsule endoscopy. The Suspected Blood Indicator (SBI) is a software feature directed to automatically detect bleeding lesions during small bowel capsule endoscopy. Objective – We aimed to assess SBI diagnostic accuracy for small bowel haemorrhage or potentially bleeding lesions during small bowel capsule endoscopy for small bowel bleeding. Methods – Single-centre retrospective study including 281 consecutive small bowel capsule endoscopy performed for small bowel bleeding during 6 years. The investigators marked lesions with high bleeding potential (P2), such as angioectasias, ulcers and tumours, as well as active bleeding during regular small bowel capsule endoscopy viewing with PillCam SB2®. All small bowel capsule endoscopy were independently reviewed by another central reader using SBI. Results – Among the 281 patients, 29 (10.3%) presented with active haemorrhage while 81 (28.9%) presented with a P2 lesion. The most frequently observed P2 lesions were angioectasias (52), ulcers (15), polyps (7) and ulcerated neoplasias (7). SBI showed a 96.6% (28/29) sensitivity for active small bowel bleeding, with a 97.7% negative predictive value. Regarding P2 lesions, the SBI displayed an overall sensitivity of 39.5%, being highest for ulcerated neoplasias (100%), but significantly lower for angioectasias (38.5%) or ulcers (20.0%). Conclusion – Although SBI sensitivity for the automatic detection of potentially bleeding lesions was low, it effectively detected active small bowel bleeding with very high sensitivity and negative predictive value.application/pdfporSuspected blood indicator in capsule endoscopy: a valuable tool for gastrointestinal bleeding diagnosisAlternativeTitlepor"Suspected Blood Indicator" na enteroscopia por cápsula: uma ferramenta útil no diagnóstico de hemorragia gastrointestinalBoal Carvalho, PedroMagalhães, JoanaDias DE Castro, FranciscaMonteiro, SaraRosa, BrunoMoreira, Maria JoãoCotter, José Almeida BerkeleyHostingInstitutionOrganizationalRepositóriUM - Universidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptPMID28079233ISSNIsPartOf0004-2803DOIIsPartOf10.1590/S0004-2803.2017v54n1-032019-01-15T17:34:25Z20172017-01-01T00:00:00ZHandlehttps://hdl.handle.net/1822/58242http://purl.org/coar/access_right/c_abf2open accessAdultEndoscopy, GastrointestinalFemaleGastrointestinal HemorrhageHumansMalePredictive Value of TestsRetrospective StudiesSensitivity and SpecificityCapsule EndoscopySmall intestine283121 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://repositorium.uminho.pt/bitstreams/525f6057-7118-4ac8-bc54-112d5b8bba49/download |
| spellingShingle | Suspected blood indicator in capsule endoscopy: a valuable tool for gastrointestinal bleeding diagnosis Boal Carvalho, Pedro Adult Endoscopy, Gastrointestinal Female Gastrointestinal Hemorrhage Humans Male Predictive Value of Tests Retrospective Studies Sensitivity and Specificity Capsule Endoscopy Small intestine |
| status | SINGLETON |
| subject.fl_str_mv | Adult Endoscopy, Gastrointestinal Female Gastrointestinal Hemorrhage Humans Male Predictive Value of Tests Retrospective Studies Sensitivity and Specificity Capsule Endoscopy Small intestine |
| title | Suspected blood indicator in capsule endoscopy: a valuable tool for gastrointestinal bleeding diagnosis |
| title_full | Suspected blood indicator in capsule endoscopy: a valuable tool for gastrointestinal bleeding diagnosis |
| title_fullStr | Suspected blood indicator in capsule endoscopy: a valuable tool for gastrointestinal bleeding diagnosis |
| title_full_unstemmed | Suspected blood indicator in capsule endoscopy: a valuable tool for gastrointestinal bleeding diagnosis |
| title_short | Suspected blood indicator in capsule endoscopy: a valuable tool for gastrointestinal bleeding diagnosis |
| title_sort | Suspected blood indicator in capsule endoscopy: a valuable tool for gastrointestinal bleeding diagnosis |
| topic | Adult Endoscopy, Gastrointestinal Female Gastrointestinal Hemorrhage Humans Male Predictive Value of Tests Retrospective Studies Sensitivity and Specificity Capsule Endoscopy Small intestine |
| topic_facet | Adult Endoscopy, Gastrointestinal Female Gastrointestinal Hemorrhage Humans Male Predictive Value of Tests Retrospective Studies Sensitivity and Specificity Capsule Endoscopy Small intestine |
| url | https://hdl.handle.net/1822/58242 |
| visible | 1 |