Publicação
Supramolecular ultra-short dehydropeptide-based hydrogels as potential affordable nanocarriers
| Resumo: | A library of Cbz-protected dehydrodipeptides was synthesised and evaluated as minimalist hydrogels. The molecular aggregation, self-assembly, gelation and biocompatibility were thoroughly studied through fluorescence spectroscopy, and the mechanical properties were assessed. The compounds that afforded hydrogels were evaluated as drug delivery systems for curcumin and doxorubicin using biomembrane models. |
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| Autores principais: | Veloso, Sérgio Rafael Silva |
| Outros Autores: | Ferreira, Paula M. T.; Castanheira, Elisabete M. S. |
| Assunto: | Hydrogels Magnetogels Drug delivery Cancer therapy Engenharia e Tecnologia::Engenharia Médica Saúde de qualidade |
| Ano: | 2021 |
| País: | Portugal |
| Tipo de documento: | outro |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| Resumo: | A library of Cbz-protected dehydrodipeptides was synthesised and evaluated as minimalist hydrogels. The molecular aggregation, self-assembly, gelation and biocompatibility were thoroughly studied through fluorescence spectroscopy, and the mechanical properties were assessed. The compounds that afforded hydrogels were evaluated as drug delivery systems for curcumin and doxorubicin using biomembrane models. |
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