Publicação
Alkaline treatments to render starch-based biodegradable polymers self-mineralizable
| Resumo: | The present research aims to develop a new route for surface functionalization of biodegradable polymers. The method is based on a wet chemistry modification, resulting in etching and/or hydrolysis in order to increase the amount of polar groups, such as hydroxyl (--OH) and carboxylic (--COOH) groups on the surface of the polymer. The polymer used as substrate was a corn starch-ethylene vinyl alcohol biodegradable blend (SEVA-C). For that purpose it was used in two different types of activation: (a) calcium hydroxide solution [Ca(OH)(2)] and (b) sodium hydroxide solution (NaOH). These treatments lead to the formation carboxylic acid-rich SEVA-C surfaces. Then, the samples were soaked in simulated body fluid (SBF) for different time periods of time until 7 days. After 1 day in SBF, the surface of SEVA-C was fully covered with spherulite particles. As the soaking time increased, the particles increased and coalesced, leading to the formation of a dense and uniform layer. Furthermore, thin-film X-ray diffraction confirms that the layer formed on the surface of the polymer was an apatite-like layer. These results suggest that this rather simple treatment is a good method for surface functionalization and subsequent mineral nucleation and growth on biodegradable polymeric surfaces to be used for bone-related applications. |
|---|---|
| Autores principais: | Leonor, I. B. |
| Outros Autores: | Kim, H-M; Balas, F.; Kawashita, M.; Reis, R. L.; Kokubo, T.; Nakamura, T. |
| Assunto: | apatite simulated body fluid (SBF) bioactivity biodegradable polymer functional groups starch-based polymers |
| Ano: | 2007 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| _version_ | 1867439159927373824 |
|---|---|
| author | Leonor, I. B. |
| author2 | Kim, H-M Balas, F. Kawashita, M. Reis, R. L. Kokubo, T. Nakamura, T. |
| author2_role | author author author author author author |
| author_facet | Leonor, I. B. Kim, H-M Balas, F. Kawashita, M. Reis, R. L. Kokubo, T. Nakamura, T. |
| author_role | author |
| contributor_name_str_mv | RepositóriUM - Universidade do Minho |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Leonor, I. B.\"},{\"Person.name\":\"Kim, H-M\"},{\"Person.name\":\"Balas, F.\"},{\"Person.name\":\"Kawashita, M.\"},{\"Person.name\":\"Reis, R. L.\"},{\"Person.name\":\"Kokubo, T.\"},{\"Person.name\":\"Nakamura, T.\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | RepositóriUM - Universidade do Minho |
| datacite.creators.creator.creatorName.fl_str_mv | Leonor, I. B. Kim, H-M Balas, F. Kawashita, M. Reis, R. L. Kokubo, T. Nakamura, T. |
| datacite.date.Accepted.fl_str_mv | 2007-01-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2012-09-13T16:08:05Z |
| datacite.date.embargoed.fl_str_mv | 2012-09-13T16:08:05Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | apatite simulated body fluid (SBF) bioactivity biodegradable polymer functional groups starch-based polymers |
| datacite.titles.title.fl_str_mv | Alkaline treatments to render starch-based biodegradable polymers self-mineralizable |
| dc.contributor.none.fl_str_mv | RepositóriUM - Universidade do Minho |
| dc.creator.none.fl_str_mv | Leonor, I. B. Kim, H-M Balas, F. Kawashita, M. Reis, R. L. Kokubo, T. Nakamura, T. |
| dc.date.Accepted.fl_str_mv | 2007-01-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2012-09-13T16:08:05Z |
| dc.date.embargoed.fl_str_mv | 2012-09-13T16:08:05Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | https://hdl.handle.net/1822/20197 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Wiley |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | apatite simulated body fluid (SBF) bioactivity biodegradable polymer functional groups starch-based polymers |
| dc.title.fl_str_mv | Alkaline treatments to render starch-based biodegradable polymers self-mineralizable |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | The present research aims to develop a new route for surface functionalization of biodegradable polymers. The method is based on a wet chemistry modification, resulting in etching and/or hydrolysis in order to increase the amount of polar groups, such as hydroxyl (--OH) and carboxylic (--COOH) groups on the surface of the polymer. The polymer used as substrate was a corn starch-ethylene vinyl alcohol biodegradable blend (SEVA-C). For that purpose it was used in two different types of activation: (a) calcium hydroxide solution [Ca(OH)(2)] and (b) sodium hydroxide solution (NaOH). These treatments lead to the formation carboxylic acid-rich SEVA-C surfaces. Then, the samples were soaked in simulated body fluid (SBF) for different time periods of time until 7 days. After 1 day in SBF, the surface of SEVA-C was fully covered with spherulite particles. As the soaking time increased, the particles increased and coalesced, leading to the formation of a dense and uniform layer. Furthermore, thin-film X-ray diffraction confirms that the layer formed on the surface of the polymer was an apatite-like layer. These results suggest that this rather simple treatment is a good method for surface functionalization and subsequent mineral nucleation and growth on biodegradable polymeric surfaces to be used for bone-related applications. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| fulltext.url.fl_str_mv | https://repositorium.uminho.pt/bitstreams/0453865a-c9bf-4e43-aa05-f7397d3fbac5/download |
| id | rum_9e91db801433da7d2e18d0624b2d5fdf |
| identifier.url.fl_str_mv | https://hdl.handle.net/1822/20197 |
| instacron_str | repositorium |
| institution | Universidade do Minho |
| instname_str | Universidade do Minho |
| language | eng |
| network_acronym_str | rum |
| network_name_str | RepositóriUM - Universidade do Minho |
| oai_identifier_str | oai:repositorium.uminho.pt:1822/20197 |
| organization_str_mv | urn:organizationAcronym:repositorium |
| person_str_mv | Leonor, I. B. Kim, H-M Balas, F. Kawashita, M. Reis, R. L. Kokubo, T. Nakamura, T. |
| publishDate | 2007 |
| publisher.none.fl_str_mv | Wiley |
| reponame_str | RepositóriUM - Universidade do Minho |
| repository_id_str | urn:repositoryAcronym:rum |
| service_str_mv | urn:repositoryAcronym:rum |
| spelling | engWileyporThe present research aims to develop a new route for surface functionalization of biodegradable polymers. The method is based on a wet chemistry modification, resulting in etching and/or hydrolysis in order to increase the amount of polar groups, such as hydroxyl (--OH) and carboxylic (--COOH) groups on the surface of the polymer. The polymer used as substrate was a corn starch-ethylene vinyl alcohol biodegradable blend (SEVA-C). For that purpose it was used in two different types of activation: (a) calcium hydroxide solution [Ca(OH)(2)] and (b) sodium hydroxide solution (NaOH). These treatments lead to the formation carboxylic acid-rich SEVA-C surfaces. Then, the samples were soaked in simulated body fluid (SBF) for different time periods of time until 7 days. After 1 day in SBF, the surface of SEVA-C was fully covered with spherulite particles. As the soaking time increased, the particles increased and coalesced, leading to the formation of a dense and uniform layer. Furthermore, thin-film X-ray diffraction confirms that the layer formed on the surface of the polymer was an apatite-like layer. These results suggest that this rather simple treatment is a good method for surface functionalization and subsequent mineral nucleation and growth on biodegradable polymeric surfaces to be used for bone-related applications.application/pdfporAlkaline treatments to render starch-based biodegradable polymers self-mineralizableLeonor, I. B.Kim, H-MBalas, F.Kawashita, M.Reis, R. L.Kokubo, T.Nakamura, T.HostingInstitutionOrganizationalRepositóriUM - Universidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptPMID18181243ISSNIsPartOf1932-7005DOIIsPartOf10.1002/term.542012-09-13T16:08:05Z20072007-01-01T00:00:00ZHandlehttps://hdl.handle.net/1822/20197http://purl.org/coar/access_right/c_abf2open accessapatitesimulated body fluid (SBF)bioactivitybiodegradable polymerfunctional groupsstarch-based polymers1033750 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://repositorium.uminho.pt/bitstreams/0453865a-c9bf-4e43-aa05-f7397d3fbac5/download |
| spellingShingle | Alkaline treatments to render starch-based biodegradable polymers self-mineralizable Leonor, I. B. apatite simulated body fluid (SBF) bioactivity biodegradable polymer functional groups starch-based polymers |
| status | SINGLETON |
| subject.fl_str_mv | apatite simulated body fluid (SBF) bioactivity biodegradable polymer functional groups starch-based polymers |
| title | Alkaline treatments to render starch-based biodegradable polymers self-mineralizable |
| title_full | Alkaline treatments to render starch-based biodegradable polymers self-mineralizable |
| title_fullStr | Alkaline treatments to render starch-based biodegradable polymers self-mineralizable |
| title_full_unstemmed | Alkaline treatments to render starch-based biodegradable polymers self-mineralizable |
| title_short | Alkaline treatments to render starch-based biodegradable polymers self-mineralizable |
| title_sort | Alkaline treatments to render starch-based biodegradable polymers self-mineralizable |
| topic | apatite simulated body fluid (SBF) bioactivity biodegradable polymer functional groups starch-based polymers |
| topic_facet | apatite simulated body fluid (SBF) bioactivity biodegradable polymer functional groups starch-based polymers |
| url | https://hdl.handle.net/1822/20197 |
| visible | 1 |