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Clinical careflows aided by uncertainty representation models

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Detalhes bibliográficos
Resumo:Choosing an appropriate support for Clinical Decision Support Systems is a complicated task, and dependent on the domain in which the system will intervene. The development of wide solutions, which are transversal to different clinical specialties, is impaired by the existence of complex decision moments that reflect the uncertainty and imprecision that are often present in these processes. The need for solutions that combine the relational nature of declarative knowledge with other models, capable of handling that uncertainty, is a necessity that current systems may be faced with. Following this line of thought, this work introduces an ontology for the representation of Clinical Practice Guidelines, with a case-study regarding colorectal cancer. It also presents two models, one based on Bayesian Networks, and another one on Artificial Neural Networks, for colorectal cancer prognosis. The objective is to observe how well these two ways of obtaining and representing knowledge are complementary, and how the machine learning models perform, attending to the available information.
Autores principais:Oliveira, Tiago José Martins
Outros Autores:Neves, João; Barbosa, Ernesto; Novais, Paulo
Assunto:Clinical decision support systems Computer-interpretable guidelines Clinical uncertainty Machine learning
Ano:2013
País:Portugal
Tipo de documento:comunicação em conferência
Tipo de acesso:acesso aberto
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
Descrição
Resumo:Choosing an appropriate support for Clinical Decision Support Systems is a complicated task, and dependent on the domain in which the system will intervene. The development of wide solutions, which are transversal to different clinical specialties, is impaired by the existence of complex decision moments that reflect the uncertainty and imprecision that are often present in these processes. The need for solutions that combine the relational nature of declarative knowledge with other models, capable of handling that uncertainty, is a necessity that current systems may be faced with. Following this line of thought, this work introduces an ontology for the representation of Clinical Practice Guidelines, with a case-study regarding colorectal cancer. It also presents two models, one based on Bayesian Networks, and another one on Artificial Neural Networks, for colorectal cancer prognosis. The objective is to observe how well these two ways of obtaining and representing knowledge are complementary, and how the machine learning models perform, attending to the available information.