Publicação
Improving the interface between orthopaedic implants and bone - a comparison between different surface treatments
| Resumo: | Orthopedic implants for load-bearing applications are usually composed of titanium-based materials. However, insufficient bioactivity of metallic materials impairs the bonding with bone, compromising osseointegration at an early stage. The implant-bone interface may be improved by regulating some surface properties of the biomaterials, including surface chemical composition, surface energy, roughness and topography, which influence the behavior of bone cells. In the present study, commercially pure titanium and Ti6Al4V alloy were used to investigate the effect of three surface treatments, after performing two different chemical pre-treatments, on the characteristics of the obtained oxide films. Regarding the pre-treatments, no major differences were observed between performing alcohol cleaning or acidic pre-treatment, considering the surface crystallinity, roughness and wettability. However, the TiO2 layer formed upon anodic oxidation, hydrothermal treatment and anodic oxidation followed by hydrothermal treatment presented different characteristics regarding its crystallinity, roughness, thickness and wettability. This study compared specific surface treatments and the hydrothermal treatment is proposed as a simple treatment capable of improving the characteristics of the implant surface, thereby promoting osteoconductivity. In fact, the culture of human Mesenchymal Stem Cells on Ti-based materials subjected to hydrothermal treatment and consequent induction of osteogenic differentiation confirm the improved surface characteristics. |
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| Autores principais: | Fonseca, Francisca Rocha Melo |
| Outros Autores: | Gasik, Michael; Pinto, Inês Mendes; Madeira, Sara Cristina Soares; Silva, Filipe Samuel; Miranda, Maria Georgina Macedo |
| Assunto: | Orthopaedic implants Titanium-based materials Surface modification techniques Osseointegration Engenharia e Tecnologia::Engenharia Mecânica |
| Ano: | 2022 |
| País: | Portugal |
| Tipo de documento: | outro |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| Resumo: | Orthopedic implants for load-bearing applications are usually composed of titanium-based materials. However, insufficient bioactivity of metallic materials impairs the bonding with bone, compromising osseointegration at an early stage. The implant-bone interface may be improved by regulating some surface properties of the biomaterials, including surface chemical composition, surface energy, roughness and topography, which influence the behavior of bone cells. In the present study, commercially pure titanium and Ti6Al4V alloy were used to investigate the effect of three surface treatments, after performing two different chemical pre-treatments, on the characteristics of the obtained oxide films. Regarding the pre-treatments, no major differences were observed between performing alcohol cleaning or acidic pre-treatment, considering the surface crystallinity, roughness and wettability. However, the TiO2 layer formed upon anodic oxidation, hydrothermal treatment and anodic oxidation followed by hydrothermal treatment presented different characteristics regarding its crystallinity, roughness, thickness and wettability. This study compared specific surface treatments and the hydrothermal treatment is proposed as a simple treatment capable of improving the characteristics of the implant surface, thereby promoting osteoconductivity. In fact, the culture of human Mesenchymal Stem Cells on Ti-based materials subjected to hydrothermal treatment and consequent induction of osteogenic differentiation confirm the improved surface characteristics. |
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