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A novel photoresponsive benzoquinolone: evaluation of the release of model amino acids

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Detalhes bibliográficos
Resumo:A photoresponsive benzoquinolone was conjugated with two model amino acids at their C-terminus, affording the corresponding ester conjugates. These ester conjugates were submitted to photocleavage studies in different mixtures of methanol/HEPES buffer solution at different wavelengths of irradiation (300, 350 and 419 nm), which confirmed the quantitative release of the model molecules in short irradiation times.
Autores principais:Soares, Ana M. S.
Outros Autores:Fonseca, Andrea Susana Cabral da; Costa, Susana P. G.; Gonçalves, M. Sameiro T.
Assunto:Quinolones Photocleavage Amino acids Photolabile protecting groups Ciências Naturais::Ciências Químicas
Ano:2015
País:Portugal
Tipo de documento:comunicação em conferência
Tipo de acesso:acesso aberto
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
Descrição
Resumo:A photoresponsive benzoquinolone was conjugated with two model amino acids at their C-terminus, affording the corresponding ester conjugates. These ester conjugates were submitted to photocleavage studies in different mixtures of methanol/HEPES buffer solution at different wavelengths of irradiation (300, 350 and 419 nm), which confirmed the quantitative release of the model molecules in short irradiation times.