Publicação

Functional Roles of Astrocyte Calcium Elevations: From Synapses to Behavior

Ver documento

Detalhes bibliográficos
Resumo:Astrocytes are fundamental players in the regulation of synaptic transmission and plasticity. They display unique morphological and phenotypical features that allow to monitor and to dynamically respond to changes. One of the hallmarks of the astrocytic response is the generation of calcium elevations, which further affect downstream cellular processes. Technical advances in the field have allowed to spatially and to temporally quantify and qualify these elevations. However, the impact on brain function remains poorly understood. In this review, we discuss evidences of the functional impact of heterogeneous astrocytic calcium events in several brain regions, and their consequences in synapses, circuits, and behavior.
Autores principais:Gomes, Sónia Isabel Nunes Guerra
Outros Autores:Sousa, Nuno; Pinto, Luísa; Oliveira, João F.
Assunto:Astrocyte Calcium Synapse Neural circuit Behavior Ciências Médicas::Medicina Básica
Ano:2018
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho

Registos relacionados

Registos relacionados