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Diversity of human papillomavirus typing among women population living in rural and remote areas of Brazilian territory

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Resumo:Genotyping HPV from samples tested positive to careHPV™ assay in rural and remote areas of Brazilian territory. Objectives Genotyping HPV from samples tested positive to careHPV™ assay in rural and remote areas of Brazilian territory. Methods A total of 5079 women were enrolled in an opportunistic screening from the Barretos Cancer Hospital, through mobile units or ambulatory unit. All careHPV™ hr-HPV positive samples were tested by a Luminex-based protocol in order to evaluate the HPV infecting types. Results Positive hr-HPV results were obtained in 10.6% (536/5068) of women. Among these cases, HPV-56 and HPV-51 were the most common types detected in 32.3% and 31.4%, respectively. HPV-53 (20.5%), HPV-18 (18.5%), HPV-58 (17.6%), HPV-52 (16.0%) and HPV-16.6%) were the other most frequent types detected. These frequencies represent prevalences of 2.35%, 2.12%, 2.02%, 1.84% and 1.80% respectively, within the population studied. Regarding low-risk HPVs, HPV-6 was detected in 12.9% of the samples. The less frequent types (<3%) were: HPV-70, HPV-11 and HPV-26. Conclusions The most frequent types detected were: HPV-56, HPV-51, HPV-53, HPV-18, HPV-58, HPV-52 and HPV-16 according to decreasing rates.
Autores principais:Lorenzi, Adriana Tarlá
Outros Autores:Fregnani, José Humberto; Villa, Luisa Lina; Sichero, Laura; Nunes, Emily Montosa; Longatto, Adhemar
Assunto:Adult Brazil DNA, Viral Early Detection of Cancer Female Genotype Human Papillomavirus DNA Tests Humans Mass Screening Middle Aged Papillomaviridae Papillomavirus Infections Public Health Surveillance Retrospective Studies Uterine Cervical Neoplasms Rural Population Cervical cancer Cervix neoplasms prevention Genotype Human papillomavirus Self-examination DNA tests Screening Ciências Médicas::Medicina Básica
Ano:2019
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho

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