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Quality of life in patients with inflammatory bowel disease: importance of clinical, demographic and psychosocial factors

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Resumo:Context - Inflammatory bowel disease causes physical and psychosocial consequences that can affect the health related quality of life. Objectives - To analyze the relationship between clinical and sociodemographic factors and quality of life in inflammatory bowel disease patients. Methods - Ninety two patients with Crohn’s disease and 58 with ulcerative colitis, filled in the inflammatory bowel disease questionnaire (IBDQ-32) and a questionnaire to collect sociodemographic and clinical data. The association between categorical variables and IBDQ-32 scores was determined using Student t test. Factors statistically significant in the univariate analysis were included in a multivariate regression model. Results - IBDQ-32 scores were significantly lower in female patients (P<0.001), patients with an individual perception of a lower co-workers support (P<0.001) and career fulfillment (P<0.001), patients requiring psychological support (P = 0.010) and pharmacological treatment for anxiety or depression (P = 0.002). A multivariate regression analysis identified as predictors of impaired HRQOL the female gender (P<0.001) and the perception of a lower co-workers support (P = 0.025) and career fulfillment (P = 0.001). Conclusion - The decrease in HRQQL was significantly related with female gender and personal perception of disease impact in success and social relations. These factors deserve a special attention, so timely measures can be implemented to improve the quality of life of patients.
Autores principais:Magalhães, Joana
Outros Autores:Castro, Francisca Dias de; Carvalho, Pedro Boal; Leite, Sílvia; Moreira, Maria João; Cotter, José Almeida Berkeley
Assunto:Inflammatory bowel diseases Crohn disease Ulcerative colitis Quality of life Questionnaires Doenças inflamatórias intestinais Doença de Crohn Colite ulcerativa Qualidade de vida Questionários
Ano:2014
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso restrito
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
Descrição
Resumo:Context - Inflammatory bowel disease causes physical and psychosocial consequences that can affect the health related quality of life. Objectives - To analyze the relationship between clinical and sociodemographic factors and quality of life in inflammatory bowel disease patients. Methods - Ninety two patients with Crohn’s disease and 58 with ulcerative colitis, filled in the inflammatory bowel disease questionnaire (IBDQ-32) and a questionnaire to collect sociodemographic and clinical data. The association between categorical variables and IBDQ-32 scores was determined using Student t test. Factors statistically significant in the univariate analysis were included in a multivariate regression model. Results - IBDQ-32 scores were significantly lower in female patients (P<0.001), patients with an individual perception of a lower co-workers support (P<0.001) and career fulfillment (P<0.001), patients requiring psychological support (P = 0.010) and pharmacological treatment for anxiety or depression (P = 0.002). A multivariate regression analysis identified as predictors of impaired HRQOL the female gender (P<0.001) and the perception of a lower co-workers support (P = 0.025) and career fulfillment (P = 0.001). Conclusion - The decrease in HRQQL was significantly related with female gender and personal perception of disease impact in success and social relations. These factors deserve a special attention, so timely measures can be implemented to improve the quality of life of patients.