Autor(es):
Ingen-Housz-Oro, S. ; Schmidt, V. ; Ameri, M. M. ; Abe, R. ; Brassard, A. ; Mostaghimi, A. ; Paller, A. S. ; Romano, A. ; Didona, B. ; Kaffenberger, B. H. ; Ben Said, B. ; Thong, B. Y. H. ; Ramsay, B. ; Brezinova, E. ; Milpied, B. ; Mortz, C. G. ; Chu, C. Y. ; Sotozono, C. ; Gueudry, J. ; Fortune, D. G. ; Dridi, S. M. ; Tartar, D. ; Do-Pham, G. ; Gabison, E. ; Phillips, E. J. ; Lewis, F. ; Salavastru, C. ; Horvath, B. ; Dart, J. ; Setterfield, J. ; Newman, J. ; Schulz, J. T. ; Delcampe, A. ; Brockow, K. ; Seminario-Vidal, L. ; Jörg, L. ; Watson, M. P. ; Gonçalo, M. ; Lucas, M. C. Marco de ; Torres, M. ; Noe, M. H. ; Hama, N. ; Shear, N. H. ; O'Reilly, P. ; Wolkenstein, P. ; Romanelli, P. ; Dodiuk-Gad, R. P. ; Micheletti, R. G. ; Tiplica, G. S. ; Sheridan, R. ; Rauz, S. ; Ahmad, S. ; Chua, S. L. ; Flynn, T. H. ; Pichler, W. ; Le, S. T. ; Maverakis, E. ; Walsh, N. ; French, L. E. ; Brüggen, M. C.
Data: 2023
Identificador Persistente: https://hdl.handle.net/10316/111619
Origem: Estudo Geral - Universidade de Coimbra
Assunto(s): Epidermal necrolysis; Stevens-Johnson syndrome; Toxic epidermal necrolysis; Sequelae; Quality of life; Delphi; Consensus; Humans; Consensus; Skin; Disease Progression; Stevens-Johnson Syndrome
Descrição
Background Long-term sequelae are frequent and often disabling after epidermal necrolysis (Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)). However, consensus on the modalities of management of these sequelae is lacking. Objectives We conducted an international multicentric DELPHI exercise to establish a multidisciplinary expert consensus to standardize recommendations regarding management of SJS/TEN sequelae. Methods Participants were sent a survey via the online tool “Survey Monkey” consisting of 54 statements organized into 8 topics: general recommendations, professionals involved, skin, oral mucosa and teeth, eyes, genital area, mental health, and allergy workup. Participants evaluated the level of appropriateness of each statement on a scale of 1 (extremely inappropriate) to 9 (extremely appropriate). Results were analyzed according to the RAND/UCLA Appropriateness Method. Results Fifty-two healthcare professionals participated. After the first round, a consensus was obtained for 100% of 54 initially proposed statements (disagreement index < 1). Among them, 50 statements were agreed upon as ‘appropriate’; four statements were considered ‘uncertain’, and ultimately finally discarded. Conclusions Our DELPHI-based expert consensus should help guide physicians in conducting a prolonged multidisciplinary follow-up of sequelae in SJS-TEN.
