Malignant angiotropic lymphoma. With primary lung involvement.

• Author(s): Glória, C ; Diogo, N ; Vilela, H ; Lopes, D ; Lopes, V
• Date: 2001
• Origin: Acta Médica Portuguesa
• Document Type: Journal article
• Language: Portuguese

Description

Angiotropic malignant lymphoma (AMLy) is a rare neoplasm characterized by the intravascular proliferation of large lymphoid cells. Most of the cases reported in the literature describe a predominant involvement of the central nervous system and skin. Although any organ may be afflicted, primary involvement of the lung is unusual. We report a case of AMLy in which the pulmonary symptoms dominate the clinical picture. The tumour cells inside the small vessels of the lung were positively identified as B-phenotype lymphoid cells by immunoperoxidase stains for CD-20, which is typical of this aggressive type of lymphoma.

Angiotropic malignant lymphoma (AMLy) is a rare neoplasm characterized by the intravascular proliferation of large lymphoid cells. Most of the cases reported in the literature describe a predominant involvement of the central nervous system and skin. Although any organ may be afflicted, primary involvement of the lung is unusual. We report a case of AMLy in which the pulmonary symptoms dominate the clinical picture. The tumour cells inside the small vessels of the lung were positively identified as B-phenotype lymphoid cells by immunoperoxidase stains for CD-20, which is typical of this aggressive type of lymphoma.