Author(s): Rebordão, Leonor ; Abreu, Ângela ; Peres, João ; J Ferreira, Joaquim
Date: 2025
Origin: Jornal da Sociedade das Ciências Médicas de Lisboa
Subject(s): Parkinson’s Disease; Rest Tremor; Cerebellar Hemorrhage
Document details
Remission of Parkinson's Disease Rest Tremor Following Cerebellar Hemorrhage
Description
Parkinson’s Disease (PD) is a clinical diagnosis that relies on the presence of bradykinesia and rigidity and/or rest tremor. Whereas the striatal dopamine depletion explains the characteristic PD symptoms such as bradykinesia and rigidity, the mechanism of tremor generation is not completely established. Mounting evidence suggests that resting tremor is associated with increased activity in a distinct cerebellothalamic circuit, which may explain its lower response to dopaminergic treatment. We describe the case of a 74-year-old man with idiopathic tremor-dominant PD who experienced rest tremor remission after cerebellar hemorrhage, supporting the role of the cerebellum in rest tremor pathophysiology.
Document Type
Journal article
Language English
Language English
