Autor(es): Sousa, MP ; Bettencourt P ; Brás-Silva C ; Pereira, C
Data: 2024
Identificador Persistente: https://hdl.handle.net/10216/156794
Origem: Repositório Aberto da Universidade do Porto
Assunto(s): Ciências da Saúde, Ciências médicas e da saúde; Health sciences, Medical and Health sciences
Heart failure (HF) is a complex clinical syndrome associated with high rates of morbidity and mortality. Over the years, it has been crucial to find accurate biomarkers capable of doing a precise monitor of HF and provide an early diagnosis. Of these, it has been established an important role of natriuretic peptides in HF assessment. Moreover, the development of biosensors has been garnering interest as new diagnostic medical tools. In this review we first provide a general overview of HF, its pathogenesis, and diagnostic features. We then discuss the role of natriuretic peptides in heart failure by characterizing them and point out their potential as biomarkers. Finally, we adress the evolution of biosensors development and the available natriuretic peptides biosensors for disease monitoring.
