Detalhes do Documento

Hepatocellular Carcinoma: An Unusual Presentation of this Rare Clinical Entity in Children

Autor(es): Martins, M ; Cardosa, MF ; Calhau, P ; Caldas, G ; Alves, R

Data: 2021

Identificador Persistente: http://hdl.handle.net/10400.17/4245

Origem: Repositório do Centro Hospitalar de Lisboa Central, EPE

Assunto(s): Abdominal Pain/etiology; Carcinoma, Hepatocellular/diagnosis; Carcinoma, Hepatocellular/ pathology; Child; HDE CIR PED


Descrição

Malignant hepatic tumors are rare in children and hepatocellular carcinomas only represent 20% of cases. A previously healthy 10 year-old male was admitted for sudden abdominal pain. Ultrasound imaging showed an ileo-ileal intussusception with spontaneous resolution, but in the face of worsening pain, fever, and a palpable epigastric mass, abdominal magnetic resonance imaging was performed, showing a liver lesion. Laboratory tests presented elevated liver enzymes and C-reactive protein, so a liver abscess was considered and treated with metronidazole plus ceftriaxone. All of the microbiology tests as well as tumoral markers were negative. Despite clinical and laboratory improvement, the lesion persisted in the imaging. A liver biopsy confirmed a hepatocellular carcinoma, and the patient was submitted to surgical resection and chemotherapy. Contrarily to adults in whom most cases are secondary to chronic liver disease, children may not have risk factors for the disease, which makes it harder to make a prompt diagnosis.

Tipo de Documento Artigo científico
Idioma Inglês
Contribuidor(es) Repositório da Unidade Local de Saúde São José
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