Author(s): Florindo, C ; Damião, V ; Lima, J ; Nogueira, I ; Rocha, I ; Caetano, P ; Ribeiro, L ; Viegas, S ; Gomes, J ; Borrego, MJ
Date: 2014
Persistent ID: http://hdl.handle.net/10400.10/1755
Origin: Repositório do Hospital Prof. Doutor Fernando Fonseca
Subject(s): Pregnancy complications; Streptococcal infections; Infectious diseases; Obstetric labor complications; Complicações do trabalho de parto; Infecções por estreptocócos
OBJECTIVE: To evaluate the positive predictive value (PPV) of group B Streptococcus (GBS) cultures at 35-37 weeks of gestation relative to GBS colonization status at delivery. METHODS: Rectovaginal swabs from 221 women at labor in four Lisbon hospitals were collected for GBS screening according to the CDC guidelines. RESULTS: The PPV was 24.4%. IAP was administered to 100% of prenatally GBS positive women. There was no case of early onset GBS disease (EOD). CONCLUSIONS: Poor accuracy of prenatal cultures in identifying true candidates for IAP highlights the need for Portuguese clinical and laboratory guidelines to prevent EOD and antibiotic overtreatment of pregnant women.
