Spatial and temporal genomic homogeneity among Haemophilus influenzae serotype f

• Author(s): Gonzalez-Diaz, Aida ; Pinto, Miguel ; Cubero, Meritxell ; Langereis, Jeroen D. ; van der Ende, Arie ; Bajanca-Lavado, Maria Paula ; Ardanuy, Carmen ; Marti, Sara
• Date: 2020
• Persistent ID: http://hdl.handle.net/10400.18/7213
• Origin: Repositório Científico do Instituto Nacional de Saúde
• Subject(s): Haemophilus influenzae; Invasive Disease; Serotype f; Infecções Respiratórias
• Document Type: Conference object
• Language: English
• Contributor(s): Repositório Científico do Instituto Nacional de Saúde

Description

Background: Haemophilus influenzae is an opportunistic pathogen highly adapted to the human respiratory tract which is often reported as the etiologic agent of infectious diseases. After the introduction of serotype b vaccine, non-typeable H. influenzae (NTHi) has become the most frequent cause of respiratory infection, followed in frequency by serotype f strains (Hif). The aim of this study was to analyze the genomic diversity among invasive and colonizing Hif isolates by whole genome sequencing (WGS).