Author(s):
Morgan, Daniel J. ; Guimaraes, Luiz H. ; Machado, Paulo Roberto Lima ; D'Oliveira Junior, Argemiro ; Almeida, Roque Pacheco de ; Lago, Ednaldo Lima ; Carvalho Filho, Edgar Marcelino de ; Faria, Daniela R. ; Tafuri, Wagner L. ; Dutra, Walderez Ornelas ; Morgan, Daniel J. ; Guimaraes, Luiz H. ; Machado, Paulo Roberto Lima ; D'Oliveira Junior, Argemiro ; Almeida, Roque Pacheco de ; Lago, Ednaldo Lima ; Carvalho Filho, Edgar Marcelino de ; Faria, Daniela R. ; Tafuri, Wagner L. ; Dutra, Walderez Ornelas
Date: 2014
Origin: Oasisbr
Subject(s): Leishmaniasis; Pregnancy; Fetal Diseases
Description
Texto completo: acesso restrito. p. 478-482
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Cutaneous leishmaniasis affects millions of people worldwide. After observations of atypical lesions in pregnant women at the health centers of Corte de Pedra, Brazil, 9 years of records were reviewed, and 26 pregnant patients were identified. A retrospective case-control study revealed that lesions in pregnant women were much larger than those in nonpregnant patients in an age- and sex-matched group (mean area, 6.08 cm2 vs. 1.46 cm2; P = .008), and many lesions had an exophytic nature. Despite foregoing treatment until after delivery, response to pentavalent antimony therapy was favorable (rate of cure with 1 course of treatment, 85%). High rates of preterm births (10.5%) and stillbirths (10.5%) were reported. Cutaneous leishmaniasis during pregnancy produces distinct lesions and may have adverse fetal effects.
